[HTML][HTML] Understanding autism spectrum disorders with animal models: applications, insights, and perspectives
Z Li, YX Zhu, LJ Gu, Y Cheng - Zoological research, 2021 - ncbi.nlm.nih.gov
Autism spectrum disorder (ASD) is typically characterized by common deficits in social skills
and repetitive/stereotyped behaviors. It is widely accepted that genetic and environmental …
and repetitive/stereotyped behaviors. It is widely accepted that genetic and environmental …
Symptomatic, genetic, and mechanistic overlaps between autism and Alzheimer's disease
Autism spectrum disorder (ASD) and Alzheimer's disease (AD) are neurodevelopmental and
neurodegenerative disorders affecting two opposite ends of life span, ie, childhood and old …
neurodegenerative disorders affecting two opposite ends of life span, ie, childhood and old …
A chromosome-level reference genome and pangenome for barn swallow population genomics
S Secomandi, GR Gallo, M Sozzoni, A Iannucci… - Cell reports, 2023 - cell.com
Insights into the evolution of non-model organisms are limited by the lack of reference
genomes of high accuracy, completeness, and contiguity. Here, we present a chromosome …
genomes of high accuracy, completeness, and contiguity. Here, we present a chromosome …
Avian models for brain mechanisms underlying altered social behavior in autism
A Csillag, Á Ádám, G Zachar - Frontiers in physiology, 2022 - frontiersin.org
The current review is an update on experimental approaches in which birds serve as model
species for the investigation of typical failure symptoms associated with autism spectrum …
species for the investigation of typical failure symptoms associated with autism spectrum …
Social stress under binge-like alcohol withdrawal in adolescence: evidence of cannabidiol effect on maladaptive plasticity in rats
A Brancato, V Castelli, G Lavanco, C D'Amico… - Psychological …, 2023 - cambridge.org
BackgroundAlcohol binge drinking may compromise the functioning of the nucleus
accumbens (NAc), ie the neural hub for processing reward and aversive responses …
accumbens (NAc), ie the neural hub for processing reward and aversive responses …
FOXP1 regulates the development of excitatory synaptic inputs onto striatal neurons and induces phenotypic reversal with reinstatement
N Khandelwal, A Kulkarni, NI Ahmed, M Harper… - Science …, 2024 - science.org
Long-range glutamatergic inputs originating from the cortex and thalamus are indispensable
for striatal development, providing the foundation for motor and cognitive functions. Despite …
for striatal development, providing the foundation for motor and cognitive functions. Despite …
Induction of an immortalized songbird cell line allows for gene characterization and knockout by CRISPR-Cas9
MT Biegler, O Fedrigo, P Collier, J Mountcastle… - Scientific Reports, 2022 - nature.com
The zebra finch is one of the most commonly studied songbirds in biology, particularly in
genomics, neuroscience and vocal communication. However, this species lacks a robust cell …
genomics, neuroscience and vocal communication. However, this species lacks a robust cell …
How thermal challenges change gene regulation in the songbird brain and gonad: Implications for sexual selection in our changing world
SE Lipshutz, CR Howell, AM Buechlein… - Molecular …, 2022 - Wiley Online Library
In a rapidly warming world, exposure to high temperatures may impact fitness, but the gene
regulatory mechanisms that link sublethal heat to sexually selected traits are not well …
regulatory mechanisms that link sublethal heat to sexually selected traits are not well …
Auditory discrimination learning and acoustic cue weighing in female zebra finches with localized FoxP1 knockdowns
Rare disruptions of the transcription factor FOXP1 are implicated in a human
neurodevelopmental disorder characterized by autism and/or intellectual disability with …
neurodevelopmental disorder characterized by autism and/or intellectual disability with …
Effects of cortical FoxP1 knockdowns on learned song preference in female zebra finches
The search for molecular underpinnings of human vocal communication has focused on
genes encoding forkhead-box transcription factors, as rare disruptions of FOXP1, FOXP2 …
genes encoding forkhead-box transcription factors, as rare disruptions of FOXP1, FOXP2 …