There has been considerable research on the biochemistry and immunology of many
human, veterinary and laboratory animal filariae, with a view to understanding pathogenic …

Human filarial infections afflict over 150 million persons worldwide and are major causes of
morbidity in many developing countries. Onchocerca volvulus infection is a leading …

We have cloned and identified the major cuticular glycoprotein (gp29) of lymphatic filarial
nematode parasites as a homolog of the antioxidant enzyme glutathione peroxidase. The …

We have isolated full-length cDNAs encoding two distinct types of CuZn superoxide
dismutases (SODs) from the filarial nematode parasite Brugia pahangi. The derived amino …

There is little information about naturally occurring protective immunity in individuals living in
areas endemic for lymphatic filariasis, though an immunologically hyperresponsive …

Despite several decades of mass drug administration and elimination-related activities,
human onchocerciasis still represents a major parasitic threat in endemic regions. Among …

A cDNA expression library constructed from RNA derived from adult stage Brugia pahangi
(mixed sexes) was screened with pooled sera from chronic, amicrofilaremic cases of human …

We have used a tag sequencing approach to survey genes expressed in the third stage
infective larvae of the human filarial nematode parasite Brugia malayi. RNA was isolated …

This book explores biochemical adaptation of helminths and protozoa and, in the authors'
own words, is an attempt to" place what is known about the biochemistry of parasites in a …

We report here a panel of cDNA clones from Onchocerca volvulus which were isolated on
the basis of being uniquely recognised by onchocerciasis sera and not by sera from patients …