MicroRNA in lung cancer: novel biomarkers and potential tools for treatment

K Inamura, Y Ishikawa - Journal of clinical medicine, 2016 - mdpi.com
Lung cancer is the leading cause of cancer death in men and women worldwide. The lack of
specific and sensitive tools for early diagnosis as well as still-inadequate targeted therapies …

MicroRNA in pancreatic cancer

K Yonemori, H Kurahara, K Maemura… - Journal of human …, 2017 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies. Patients
with PDAC are often asymptomatic, and many have lymph node and distant metastases as …

Tumor necrosis factor α suppresses the mesenchymal stem cell osteogenesis promoter miR‐21 in estrogen deficiency–induced osteoporosis

N Yang, G Wang, C Hu, Y Shi, L Liao… - Journal of Bone and …, 2013 - academic.oup.com
Inflammatory cytokines, especially tumor necrosis factor α (TNF‐α), have been shown to
inhibit osteogenic differentiation of mesenchymal stem cells (MSCs) and bone formation in …

MiR-21 overexpression is associated with acquired resistance of EGFR-TKI in non-small cell lung cancer

B Li, S Ren, X Li, Y Wang, D Garfield, S Zhou, X Chen… - Lung cancer, 2014 - Elsevier
Background and purpose With the increasing use of epidermal growth factor receptor
tyrosine kinase inhibitor (EGFR TKI) in patients with advanced non-small cell lung cancer …

MicroRNAs cooperatively inhibit a network of tumor suppressor genes to promote pancreatic tumor growth and progression

AE Frampton, L Castellano, T Colombo, E Giovannetti… - Gastroenterology, 2014 - Elsevier
Background & Aims There has not been a broad analysis of the combined effects of altered
activities of microRNAs (miRNAs) in pancreatic ductal adenocarcinoma (PDAC) cells, and it …

Silencing of microRNA‐21 in vivo ameliorates autoimmune splenomegaly in lupus mice

BG Garchow, O Bartulos Encinas, YT Leung… - EMBO molecular …, 2011 - embopress.org
MicroRNAs (miRNAs) have been implicated in B cell lineage commitment, regulation of T
cell differentiation, TCR signalling, regulation of IFN signalling, and numerous other …

MiR-130b is a prognostic marker and inhibits cell proliferation and invasion in pancreatic cancer through targeting STAT3

G Zhao, J Zhang, Y Shi, Q Qin, Y Liu, B Wang, K Tian… - PloS one, 2013 - journals.plos.org
Accumulating evidence indicates that microRNAs (miRNAs) are aberrantly expressed in
human cancer and contribute to the tumorigenesis, but their roles in pancreatic cancer are …

MicroRNA-21 down-regulates inflammation and inhibits periodontitis

W Zhou, L Su, X Duan, X Chen, A Hays… - Molecular …, 2018 - Elsevier
Periodontitis is one of the most prevalent inflammatory diseases, characterized by gingival
inflammation and alveolar bone loss. MicroRNAs (MiRNAs) are important regulators of …

Major tumor suppressor and oncogenic non-coding RNAs: clinical relevance in lung cancer

K Inamura - Cells, 2017 - mdpi.com
Lung cancer is the leading cause of cancer deaths worldwide, yet there remains a lack of
specific and sensitive tools for early diagnosis and targeted therapies. High-throughput …

[HTML][HTML] microRNAs with prognostic significance in pancreatic ductal adenocarcinoma: A meta-analysis

AE Frampton, J Krell, NB Jamieson, TMH Gall… - European journal of …, 2015 - Elsevier
Background Reports have described the prognostic relevance of microRNAs (miRNAs) in
patients treated for pancreatic ductal adenocarcinoma (PDAC). However, many of these …