Self-assembled peptide nanostructures for ECM biomimicry

D Marin, S Marchesan - Nanomaterials, 2022 - mdpi.com
Proteins are functional building blocks of living organisms that exert a wide variety of
functions, but their synthesis and industrial production can be cumbersome and expensive …

Novel gels: an emerging approach for delivering of therapeutic molecules and recent trends

TK Sastri, VN Gupta, S Chakraborty, S Madhusudhan… - Gels, 2022 - mdpi.com
Gels are semisolid, homogeneous systems with continuous or discrete therapeutic
molecules in a suitable lipophilic or hydrophilic three-dimensional network base. Innovative …

The Design of a Participatory Peptide Nucleic Acid Duplex Crosslinker to Enhance the Stiffness of Self‐Assembled Peptide Gels

S Sarkar, CF Anderson, JP Schneider - Angewandte Chemie, 2024 - Wiley Online Library
Herein, peptide nucleic acids (PNAs) are employed in the design of a participatory duplex
PNA‐peptide crosslinking agent. Biophysical and mechanical studies show that crosslinkers …

Ag/Poly(N-isopropylacrylamide)-laponite Hydrogel Surface-Enhanced Raman Membrane Substrate for Rapid Separation, Concentration and Detection of Hydrophilic …

R Su, G Li, X Xiao - Analytical Chemistry, 2023 - ACS Publications
In this work, Ag nanoparticles (AgNPs) were embedded into a poly (N-isopropylacrylamide)-
laponite (Ag/PNIP-LAP) hydrogel membrane for highly sensitive surface-enhancement …

Hydrogel scaffolds in the treatment of spinal cord injury: a review

M Cai, L Chen, T Wang, Y Liang, J Zhao… - Frontiers in …, 2023 - frontiersin.org
Spinal cord injury (SCI) is a disease of the central nervous system often caused by
accidents, and its prognosis is unsatisfactory, with long-term adverse effects on patients' …

Histidine-containing amphiphilic peptide-based non-cytotoxic hydrogelator with antibacterial activity and sustainable drug release

B Hansda, J Majumder, B Mondal, A Chatterjee, S Das… - Langmuir, 2023 - ACS Publications
A histidine-based amphiphilic peptide (P) has been found to form an injectable transparent
hydrogel in phosphate buffer solution over a pH range from 7.0 to 8.5 with an inherent …

[HTML][HTML] Biodegradable Natural Hydrogels for Tissue Engineering, Controlled Release, and Soil Remediation

A Garcia-Garcia, S Muñana-González… - Polymers, 2024 - mdpi.com
This article provides insights into hydrogels of the most promising biodegradable natural
polymers and their mechanisms of degradation, highlighting the different possibilities of …

Structure of Amyloid Peptide Ribbons Characterized by Electron Microscopy, Atomic Force Microscopy, and Solid-State Nuclear Magnetic Resonance

KR Thurber, WM Yau, R Tycko - The Journal of Physical Chemistry …, 2024 - ACS Publications
Polypeptides often self-assemble to form amyloid fibrils, which contain cross-β structural
motifs and are typically 5–15 nm in width and micrometers in length. In many cases, short …

Orthogonal Self-Assembly of Amphiphilic Peptide Hydrogels and Liposomes Results in Composite Materials with Tunable Release Profiles

JWR Swain, CY Yang, JD Hartgerink - Biomacromolecules, 2023 - ACS Publications
Self-assembled nanomaterials are promising candidates for drug delivery by providing a
higher degree of spatiotemporal control compared to free drugs. However, challenges such …

Substance P‐Derived Extracellular‐Matrix‐Mimicking Peptide Hydrogel as a Cytocompatible Biomaterial Platform

N Mukherjee, S Ghosh - ChemBioChem, 2023 - Wiley Online Library
Self‐assembled short peptide‐based hydrogel platforms have become widely applicable
biomedical therapeutic maneuvers for their soft, tunable architecture, which can influence …