This review provides an updated summary of the state of our knowledge of the genetic
contributions to the pathogenesis of congenital heart disease. Since 2007, when the initial …

Zebrafish (Danio rerio) has been a prominent model vertebrate in a variety of biological
disciplines. Substantial information gathered from developmental and genetic research …

The mesencephalic locomotor region (MLR) is a brain stem area whose stimulation triggers
graded forward locomotion. How MLR neurons recruit downstream vsx2+(V2a) …

Room temperature liquid metals (LMs) represent a class of emerging multifunctional
materials with attractive novel properties. Here, we show that photopolymerized LMs present …

Correlative evidence suggests that polyploidization of heart muscle, which occurs naturally
in post-natal mammals, creates a barrier to heart regeneration. Here, we move beyond a …

The type II bacterial CRISPR/Cas9 system is rapidly becoming popular for genome-
engineering due to its simplicity, flexibility and high efficiency. Recently, targeted knock-in of …

Transgenesis is an important tool for assessing gene function. In zebrafish, transgenesis has
suffered from three problems: the labor of building complex expression constructs using …

Severe traumatic injury to the adult mammalian CNS leads to life-long loss of function. By
contrast, several non-mammalian vertebrate species, including adult zebrafish, have a …

Recent evidence indicates that acquisition of artery or vein identity during vascular
development is governed, in part, by genetic mechanisms. The artery-specific expression of …

Despite decades of intensive investigation, important questions remain regarding the
functional, ecological, and evolutionary roles of heat shock proteins. In this paper, we …