Crimean-Congo hemorrhagic fever virus: current advances and future prospects of antiviral strategies

S Dai, F Deng, H Wang, Y Ning - Viruses, 2021 - mdpi.com
Crimean-Congo hemorrhagic fever virus (CCHFV) is a widespread, tick-borne pathogen that
causes Crimean-Congo hemorrhagic fever (CCHF) with high morbidity and mortality …

Recent Advances in Crimean-Congo Hemorrhagic Fever Virus Detection, Treatment, and Vaccination: Overview of Current Status and Challenges

K Muzammil, S Rayyani, A Abbas Sahib… - Biological Procedures …, 2024 - Springer
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne virus, and zoonosis, and
affects large regions of Asia, Southwestern and Southeastern Europe, and Africa. CCHFV …

Differential cell line susceptibility to Crimean-Congo hemorrhagic fever virus

S Dai, Q Wu, X Wu, C Peng, J Liu, S Tang… - Frontiers in Cellular …, 2021 - frontiersin.org
Crimean-Congo hemorrhagic fever (CCHF) is a severe tick-borne viral disease of global
concerns due to the increasing incidence and lack of effective treatments. The causative …

Degenerate sequence-based CRISPR diagnostic for Crimean–Congo hemorrhagic fever virus

H Li, A Bello, G Smith, DMS Kielich… - PLoS neglected …, 2022 - journals.plos.org
CRISPR (clustered regularly interspaced short palindromic repeats), an ancient defense
mechanism used by prokaryotes to cleave nucleic acids from invading viruses and plasmids …

COVID-19 vaccine design using reverse and structural vaccinology, ontology-based literature mining and machine learning

A Huffman, E Ong, J Hur, A D'Mello… - Briefings in …, 2022 - academic.oup.com
Rational vaccine design, especially vaccine antigen identification and optimization, is critical
to successful and efficient vaccine development against various infectious diseases …

Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target

U Neogi, N Elaldi, S Appelberg, A Ambikan, E Kennedy… - Elife, 2022 - elifesciences.org
The pathogenesis and host-viral interactions of the Crimean–Congo hemorrhagic fever
orthonairovirus (CCHFV) are convoluted and not well evaluated. Application of the multi …

[HTML][HTML] Transcriptome profiling highlights regulated biological processes and type III interferon antiviral responses upon Crimean-Congo hemorrhagic fever virus …

Q Mo, K Feng, S Dai, Q Wu, Z Zhang, A Ali, F Deng… - Virologica Sinica, 2023 - Elsevier
Crimean-Congo hemorrhagic fever virus (CCHFV) is a biosafety level-4 (BSL-4) pathogen
that causes Crimean-Congo hemorrhagic fever (CCHF) characterized by hemorrhagic …

Host response transcriptomic analysis of Crimean-Congo hemorrhagic fever pathogenesis in the cynomolgus macaque model

CE Arnold, CJ Shoemaker, DR Smith, CE Douglas… - Scientific Reports, 2021 - nature.com
Crimean-Congo hemorrhagic fever virus (CCHFV) is a highly pathogenic tick-borne RNA
virus prevalent in Asia, Europe, and Africa, and can cause a hemorrhagic disease (CCHF) in …

Distinguishing host responses, extensive viral dissemination and long-term viral RNA persistence in domestic sheep experimentally infected with Crimean-Congo …

H Li, M Pinette, G Smith, M Goolia… - Emerging Microbes & …, 2024 - Taylor & Francis
Crimean-Congo haemorrhagic fever orthonairovirus (CCHFV) is a tick-borne, risk group 4
pathogen that often causes a severe haemorrhagic disease in humans (CCHF) with high …

The relationship between DUGBE virus infection and autophagy in epithelial cells

M Moroso, A Rozières, P Verlhac, F Komurian-Pradel… - Viruses, 2022 - mdpi.com
Dugbe orthonairovirus (DUGV) is a tick-borne arbovirus within the order Bunyavirales.
Although displaying mild pathogenic potential, DUGV is genetically related to the Crimean …