Implementation of biomarkers in sepsis and septic shock in emergency situations, remains
highly challenging. This viewpoint arose from a public–private 3-day workshop aiming to …

The complement system, comprising over 30 proteins, is integral to the immune system, and
the coagulation system is critical for vascular homeostasis. The activation of the complement …

Sepsis is the leading cause of death of hospitalized children worldwide. Despite the
established link between immune dysregulation and mortality in pediatric sepsis, it remains …

Mitochondrial dysfunction is a recognized feature of sepsis, characterized by ultrastructural
damage, diminished oxidative phosphorylation, and depletion of mitochondrial antioxidant …

Critical illness, a state of health instability and organ dysfunction necessitating urgent
medical attention, is often characterized by dysregulated immune responses, which can …

The major challenges related to surgical infections are not the need to elucidate new
therapeutic targets or develop innovative technology but rather to utilize our currently …