The global challenge to the treatment of malaria is mainly the occurrence of resistance of
malaria parasites to conventionally used antimalarials. Artesunate, a semisynthetic …

Water solubility and low bioavailability of active pharmaceutical ingredients are some of the
main challenges in the process of developing new drugs, especially drugs in oral solid …

Co-crystallization is a promising approach for improving physical and pharmacological
properties of API, viz., solubility, dissolution rate, stability, hygroscopicity, tablet ability …

Many active ingredients from traditional Chinese medicine (TCM) exhibit poor
pharmaceutical properties (eg, low aqueous solubility, slow dissolution, low bioavailability …

Objective: The focus of this study is to develop the formation mefenamic acid (MFA)-
nicotinamide (NCT) co-crystal by using melt crystallization method and investigate its …

Ko-amorf adalah suatu sistem multikomponen padat yang mengandung zat aktif dan
molekul dengan berat molekul rendah lainnya (koformer) yang dapat berupa eksipien atau …

Objective: This study aimed to improve the solubility of Ketoprofen, a non-steroidal anti-
inflammatory drug (NSAID) that belongs to the Biopharmaceutical Classification System …

Kokristal merupakan cara alternatif yang dapat dilakukan untuk meningkatkan kemampuan
melarut obat yang sukar larut dalam air dan meningkatkan bioavailabilitas obat yang buruk …

Enhancing the physicochemical properties of active pharmaceutical ingredients (APIs) has
been achieved by utilizing solid modification through the formation of co-crystals. Co-crystal …

Piperin adalah metabolit sekunder golongan alkaloid yang ditemukan pada spesies Piper
nigrum dan Piperi retrofractum, dan menunjukan berbagai aktivitas farmakologi, termasuk …