Toll-like receptors in immunity and inflammatory diseases: Past, present, and future

K Vijay - International immunopharmacology, 2018 - Elsevier
The immune system is a very diverse system of the host that evolved during evolution to
cope with various pathogens present in the vicinity of environmental surroundings inhabited …

A double-edged sword of immuno-microenvironment in cardiac homeostasis and injury repair

K Sun, Y Li, J Jin - Signal transduction and targeted therapy, 2021 - nature.com
The response of immune cells in cardiac injury is divided into three continuous phases:
inflammation, proliferation and maturation. The kinetics of the inflammatory and proliferation …

Evolutionary constraint and innovation across hundreds of placental mammals

MJ Christmas, IM Kaplow, DP Genereux, MX Dong… - Science, 2023 - science.org
Zoonomia is the largest comparative genomics resource for mammals produced to date. By
aligning genomes for 240 species, we identify bases that, when mutated, are likely to affect …

RNA m6A methylation orchestrates cancer growth and metastasis via macrophage reprogramming

H Yin, X Zhang, P Yang, X Zhang, Y Peng, D Li… - Nature …, 2021 - nature.com
Abstract N6-methyladenosine (m6A) is a reversible mRNA modification that has been shown
to play important roles in various biological processes. However, the roles of m6A …

Review of cadmium toxicity effects on fish: Oxidative stress and immune responses

JW Lee, AH Jo, DC Lee, CY Choi, JC Kang… - Environmental research, 2023 - Elsevier
Cadmium (Cd) in aquatic environments can cause environmental toxicity to fish and induce
oxidative stress owing to an excessive production of reactive oxygen species in fish bodies …

A comparison of the innate and adaptive immune systems in cartilaginous fish, ray-finned fish, and lobe-finned fish

NC Smith, ML Rise, SL Christian - Frontiers in immunology, 2019 - frontiersin.org
The immune system is composed of two subsystems—the innate immune system and the
adaptive immune system. The innate immune system is the first to respond to pathogens and …

Protecting the newborn and young infant from infectious diseases: lessons from immune ontogeny

TR Kollmann, B Kampmann, SK Mazmanian… - Immunity, 2017 - cell.com
Infections in the first year of life are common and often severe. The newborn host
demonstrates both quantitative and qualitative differences to the adult in nearly all aspects of …

Origins, biology, and diseases of tissue macrophages

N Cox, M Pokrovskii, R Vicario… - Annual review of …, 2021 - annualreviews.org
Tissue-resident macrophages are present in most tissues with developmental, self-renewal,
or functional attributes that do not easily fit into a textbook picture of a plastic and …

Structure of fish Toll-like receptors (TLR) and NOD-like receptors (NLR)

BR Sahoo - International journal of biological macromolecules, 2020 - Elsevier
Innate immunity driven by pattern recognition receptor (PRR) protects the host from invading
pathogens. Aquatic animals like fish where the adaptive immunity is poorly developed …

Microplastic pollution as a grand challenge in marine research: a closer look at their adverse impacts on the immune and reproductive systems

M Sharifinia, ZA Bahmanbeigloo… - Ecotoxicology and …, 2020 - Elsevier
Microplastic (MP) pollution of the marine environment is now a growing global concern
posing a threat to a variety of species through the ingestion and transfer within food webs …