Ginsenoside Rg1 as an effective regulator of mesenchymal stem cells

F He, C Yu, T Liu, H Jia - Frontiers in Pharmacology, 2020 - frontiersin.org
Recently, breakthroughs have been made in the use of mesenchymal stem cells (MSCs) to
treat various diseases. Several stem cell types have been authorized as drugs by the …

Natural compounds and mesenchymal stem cells: implications for inflammatory-impaired tissue regeneration

W Li, Z Xiang, W Yu, X Huang, Q Jiang… - Stem Cell Research & …, 2024 - Springer
Inflammation is a common and important pathological process occurring in any part of the
body and relating to a variety of diseases. Effective tissue repair is critical for the survival of …

[HTML][HTML] Nano-hydroxyapatite bone scaffolds with different porous structures processed by digital light processing 3D printing

H Liang, Y Wang, S Chen, Y Liu, Z Liu… - International Journal of …, 2022 - ncbi.nlm.nih.gov
The morphologies and structures of the scaffold have a significant influence on their
mechanical and biological properties. In this work, different types of porous structures: Triply …

Inhibitory role of ginsenoside Rb2 in endothelial senescence and inflammation mediated by microRNA‑216a

Y Chen, S Wang, S Yang, R Li… - Molecular …, 2021 - spandidos-publications.com
Targeting microRNAs (miRs) using small chemical molecules has become a promising
strategy for disease treatment. miR‑216a has been reported to be a potential therapeutic …

Combined analysis of surface protein profile and microRNA expression profile of exosomes derived from brain microvascular endothelial cells in early cerebral …

D Yang, Z Li, G Gao, X Li, Z Liao, Y Wang, W Li… - ACS …, 2021 - ACS Publications
Endothelial cell damage is an important pathological basis for the deterioration of acute
ischemia stroke. Our previous studies have been exploring the mechanism of blood–brain …

The mechanism by which miR-494-3p regulates PGC1-α-mediated inhibition of mitophagy in cardiomyocytes and alleviation of myocardial ischemia—reperfusion …

N Mu, T Zhang, Y Zhu, B Lu, Q Zheng… - BMC Cardiovascular …, 2023 - Springer
Objective The purpose of this study was to explore whether miR-494-3p inhibits the
occurrence of mitochondrial autophagy in cardiomyocytes by inhibiting the expression of …

Ginsenoside Rg1 protects against hind-limb ischemia reperfusion induced lung injury via NF-κB/COX-2 signaling pathway

Y Ye, Y Shan, C Bao, Y Hu, L Wang - International Immunopharmacology, 2018 - Elsevier
Abstract Background/aims Ginsenoside Rg1 is regarded as the primary bioactive ingredient
in Panax notoginseng that has been well recognized for its protective effects against …

Strontium modified calcium sulfate hemihydrate scaffold incorporating ginsenoside Rg1/gelatin microspheres for bone regeneration

P Luo, L Yu, Q Lin, C Wang, D Yang… - … in Bioengineering and …, 2020 - frontiersin.org
The aim of this study was to prepare a promising biomaterial for bone tissue repair and
regeneration. The Strontium–calcium sulfate hemihydrate (Sr-α-CaS) scaffold incorporating …

MicroRNA‑494‑3p protects rat cardiomyocytes against septic shock via PTEN

P Wu, L Kong, J Li - Experimental and therapeutic …, 2019 - spandidos-publications.com
The aim of the present study was to investigate the role of microRNA (miR)‑494‑3p in
myocardial injury in patients with septic shock and the underlying mechanism. A total of 22 …

Bone transport induces the release of factors with multi-tissue regenerative potential for diabetic wound healing in rats and patients

J Xie, X Liu, B Wu, B Chen, Q Song, Y Guan… - Cell Reports …, 2024 - cell.com
Tibial cortex transverse distraction is a surgical method for treating severe diabetic foot
ulcers (DFUs), but the underlying mechanism is unclear. We show that antioxidant proteins …