Digestive cancers are the leading cause of cancer-related death worldwide and have high
risks of morbidity and mortality. Histone methylation, which is mediated mainly by lysine …

The occurrence of cancer entails a series of genetic mutations that favor uncontrollable
tumor growth. It is believed that various factors collectively contribute to cancer, and there is …

Background There is a critical need for objective and reliable biomarkers of outcome in
meningiomas beyond WHO classification. Loss of H3K27me3 has been reported as a …

HOX transcript antisense intergenic RNA (HOTAIR), a well-known long non-coding RNA,
plays an important role in the regulation of epithelial-to-mesenchymal transition (EMT). In …

Epithelial–mesenchymal transition (EMT) is an essential process for morphogenesis and
organ development which reversibly enables polarized epithelial cells to lose their epithelial …

Simple Summary Regulation of gene expression is important for appropriate cell
development but can also lead to inappropriate cell transformation resulting in cancer …

Osteosarcoma is the most frequent type of bone cancer found in children and adolescents,
and commonly arises in the metaphyseal region of tubular long bones. Standard therapeutic …

Loss of E-cadherin and epithelial to mesenchymal transition (EMT) are key steps in cancer
progression. Reactive oxygen species (ROS) play significant roles in cellular physiology and …

Background Gastrointestinal malignancies encompass a diverse group of cancers that pose
significant challenges to global health. The major histocompatibility complex (MHC) plays a …

Gastric adenocarcinoma (GAC) is the third leading cause of cancer-related death worldwide.
A high mortality rate and resistance to treatment protocols due to a heterogeneous …