Ivermectin for preventing and treating COVID‐19

M Popp, M Stegemann, MI Metzendorf… - Cochrane Database …, 2021 - cochranelibrary.com
Background Ivermectin, an antiparasitic agent used to treat parasitic infestations, inhibits the
replication of viruses in vitro. The molecular hypothesis of ivermectin's antiviral mode of …

Convalescent plasma or hyperimmune immunoglobulin for people with COVID‐19: a living systematic review

I Monsef, C Doree, EM Wood… - Cochrane Database …, 2020 - cochranelibrary.com
Background Convalescent plasma and hyperimmune immunoglobulin may reduce mortality
in patients with viral respiratory diseases, and are currently being investigated in trials as …

SARS‐CoV‐2‐neutralising monoclonal antibodies for treatment of COVID‐19

KL Chai, E Tomlinson, Z Khosravi… - Cochrane Database …, 2021 - cochranelibrary.com
Background Monoclonal antibodies (mAbs) are laboratory‐produced molecules derived
from the B cells of an infected host. They are being investigated as a potential therapy for …

Negative pressure wound therapy for surgical wounds healing by primary closure

G Norman, C Shi, EL Goh, EM Murphy… - Cochrane Database …, 2022 - cochranelibrary.com
Background Indications for the use of negative pressure wound therapy (NPWT) are broad
and include prophylaxis for surgical site infections (SSIs). Existing evidence for the …

Nirmatrelvir combined with ritonavir for preventing and treating COVID‐19

S Reis, MI Metzendorf, R Kuehn… - Cochrane Database …, 2023 - cochranelibrary.com
Background Oral nirmatrelvir/ritonavir (Paxlovid) aims to avoid severe COVID‐19 in
asymptomatic people or those with mild symptoms, thereby decreasing hospitalization and …

Anticoagulants for people hospitalised with COVID‐19

RLG Flumignan, VT Civile… - Cochrane Database …, 2022 - cochranelibrary.com
Background The primary manifestation of coronavirus disease 2019 (COVID‐19) is
respiratory insufficiency that can also be related to diffuse pulmonary microthrombosis and …

Antiepileptic drug monotherapy for epilepsy: a network meta‐analysis of individual participant data

SJ Nevitt, M Sudell, S Cividini… - Cochrane Database …, 2022 - cochranelibrary.com
Objectives To compare the time to treatment failure, remission and first seizure of 12 AEDs
(carbamazepine, phenytoin, sodium valproate, phenobarbitone, oxcarbazepine, lamotrigine …

Psychological interventions to foster resilience in healthcare professionals

AM Kunzler, I Helmreich, A Chmitorz… - Cochrane Database …, 2020 - cochranelibrary.com
Background Resilience can be defined as the maintenance or quick recovery of mental
health during or after periods of stressor exposure, which may result from a potentially …

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia

Q Zhang, C Li, HV Worthington… - Cochrane Database of …, 2020 - cochranelibrary.com
Background Ventilator‐associated pneumonia (VAP) is defined as pneumonia developing in
people who have received mechanical ventilation for at least 48 hours. VAP is a potentially …

Interventions for managing medication‐related osteonecrosis of the jaw

NH Beth-Tasdogan, B Mayer… - Cochrane Database …, 2022 - cochranelibrary.com
Background Medication‐related osteonecrosis of the jaw (MRONJ) is a severe adverse
reaction experienced by some individuals to certain medicines commonly used in the …