Gut microbial molecules in behavioural and neurodegenerative conditions

BD Needham, R Kaddurah-Daouk… - Nature Reviews …, 2020 - nature.com
Mounting evidence suggests that the gut microbiome impacts brain development and
function. Gut–brain connections may be mediated by an assortment of microbial molecules …

The ever-changing roles of serotonin

LA Jones, EW Sun, AM Martin, DJ Keating - The international journal of …, 2020 - Elsevier
Abstract Serotonin (5-HT) has traditional roles as a key neurotransmitter in the central
nervous system and as a regulatory hormone controlling a broad range of physiological …

The gut microbiome and mental health: advances in research and emerging priorities

AP Shoubridge, JM Choo, AM Martin, DJ Keating… - Molecular …, 2022 - nature.com
The gut microbiome exerts a considerable influence on human neurophysiology and mental
health. Interactions between intestinal microbiology and host regulatory systems have now …

The outer membrane protein Amuc_1100 of Akkermansia muciniphila promotes intestinal 5-HT biosynthesis and extracellular availability through TLR2 signalling

J Wang, W Xu, R Wang, R Cheng, Z Tang, M Zhang - Food & Function, 2021 - pubs.rsc.org
Akkermansia muciniphila is a probiotic inhabiting host intestinal mucus layers and displays
evident easing or therapeutic effects on host enteritis and metabolic disorders such as …

[PDF][PDF] Interleukin-33 promotes serotonin release from enterochromaffin cells for intestinal homeostasis

Z Chen, J Luo, J Li, G Kim, A Stewart, JF Urban… - Immunity, 2021 - cell.com
The gastrointestinal tract is known as the largest endocrine organ that encounters and
integrates various immune stimulations and neuronal responses due to constant …

[HTML][HTML] Tryptophan‐derived serotonin‐kynurenine balance in immune activation and intestinal inflammation

S Haq, JA Grondin, WI Khan - The FASEB Journal, 2021 - ncbi.nlm.nih.gov
Endogenous tryptophan metabolism pathways lead to the production of serotonin (5‐
hydroxytryptamine; 5‐HT), kynurenine, and several downstream metabolites which are …

Influence of the microbiota-gut-brain axis on behavior and welfare in farm animals: A review

N Kraimi, M Dawkins, SG Gebhardt-Henrich… - Physiology & …, 2019 - Elsevier
There is increasing evidence of a pivotal role of the gut microbiota (GUT-M) in key
physiological functions in vertebrates. Many studies discuss functional implications of the …

[HTML][HTML] Crosstalk between intestinal serotonergic system and pattern recognition receptors on the microbiota–gut–brain axis

E Layunta, B Buey, JE Mesonero… - Frontiers in …, 2021 - frontiersin.org
Disruption of the microbiota–gut–brain axis results in a wide range of pathologies that are
affected, from the brain to the intestine. Gut hormones released by enteroendocrine cells to …

[HTML][HTML] The role of the intestinal epithelium in the “weep and sweep” response during gastro—intestinal helminth infections

P Bąska, LJ Norbury - Animals, 2022 - mdpi.com
Simple Summary The immune system actively combats intruders such as bacteria, viruses,
fungi, and protozoan and metazoan parasites using leukocytes. During an infection white …

Increased gut serotonin production in response to bisphenol A structural analogs may contribute to their obesogenic effects

NG Barra, YH Kwon, KM Morrison… - American Journal …, 2022 - journals.physiology.org
Obesogens are synthetic, environmental chemicals that can disrupt endocrine control of
metabolism and contribute to the risk of obesity and metabolic disease. Bisphenol A (BPA) is …