Using MetaboAnalyst 3.0 for comprehensive metabolomics data analysis

J Xia, DS Wishart - Current protocols in bioinformatics, 2016 - Wiley Online Library
Abstract MetaboAnalyst (http://www. metaboanalyst. ca) is a comprehensive Web application
for metabolomic data analysis and interpretation. MetaboAnalyst handles most of the …

Biochemical and clinical impact of organic uremic retention solutes: a comprehensive update

R Vanholder, A Pletinck, E Schepers, G Glorieux - Toxins, 2018 - mdpi.com
In this narrative review, the biological/biochemical impact (toxicity) of a large array of known
individual uremic retention solutes and groups of solutes is summarized. We classified these …

Using MetaboAnalyst 4.0 for comprehensive and integrative metabolomics data analysis

J Chong, DS Wishart, J Xia - Current protocols in bioinformatics, 2019 - Wiley Online Library
Abstract MetaboAnalyst (https://www. metaboanalyst. ca) is an easy‐to‐use web‐based tool
suite for comprehensive metabolomic data analysis, interpretation, and integration with other …

Renal fibrosis: novel insights into mechanisms and therapeutic targets

P Boor, T Ostendorf, J Floege - Nature Reviews Nephrology, 2010 - nature.com
Renal fibrosis is the common end point of virtually all progressive kidney diseases. Renal
fibrosis should not be viewed as a simple and uniform'scar', but rather as a dynamic system …

Chemometrics in metabolomics—a review in human disease diagnosis

R Madsen, T Lundstedt, J Trygg - Analytica chimica acta, 2010 - Elsevier
Metabolomics is a post genomic research field concerned with developing methods for
analysis of low molecular weight compounds in biological systems, such as cells, organs or …

Hippurate: the natural history of a mammalian–microbial cometabolite

HJ Lees, JR Swann, ID Wilson… - Journal of proteome …, 2013 - ACS Publications
Hippurate, the glycine conjugate of benzoic acid, is a normal constituent of the endogenous
urinary metabolite profile and has long been associated with the microbial degradation of …

Metabolomic data processing, analysis, and interpretation using MetaboAnalyst

J Xia, DS Wishart - Current protocols in bioinformatics, 2011 - Wiley Online Library
MetaboAnalyst is a comprehensive, Web‐based tool designed for processing, analyzing,
and interpreting metabolomic data. It handles most of the common metabolomic data types …

[HTML][HTML] Gene and protein expressions and metabolomics exhibit activated redox signaling and wnt/β-catenin pathway are associated with metabolite dysfunction in …

DQ Chen, G Cao, H Chen, D Liu, W Su, XY Yu… - Redox biology, 2017 - Elsevier
Abstract Changes in plasma concentration of small organic metabolites could be due to their
altered production or urinary excretion and changes in their urine concentration may be due …

Metabolomics in chronic kidney disease

YY Zhao - Clinica chimica acta, 2013 - Elsevier
Chronic kidney disease (CKD) represents a major challenge to public healthcare.
Traditional clinical biomarkers of renal function (blood urea nitrogen and serum creatinine) …

Current mathematical methods used in QSAR/QSPR studies

P Liu, W Long - International Journal of Molecular Sciences, 2009 - mdpi.com
This paper gives an overview of the mathematical methods currently used in quantitative
structure-activity/property relationship (QASR/QSPR) studies. Recently, the mathematical …