α-Synuclein is an abundant neuronal protein that is highly enriched in presynaptic nerve
terminals. Genetics and neuropathology studies link α-synuclein to Parkinson's disease (PD) …

Abstract α-Synuclein is an abundant neuronal protein which localizes predominantly to
presynaptic terminals, and is strongly linked genetically and pathologically to Parkinson's …

Bile acids are a group of molecular species of acidic steroids with peculiar physical-
chemical and biological characteristics. At high concentrations they become toxic to …

Abstract α-Synuclein is a small protein that has special relevance for understanding
Parkinson disease and related disorders. Not only is α-synuclein found in Lewy bodies …

There is increasing evidence of prodromal manifestation of neuropsychiatric symptoms in a
variety of neurodegenerative diseases such as Parkinson's disease (PD) and Huntington's …

Matrix metalloproteinases (MMPs), originally discovered to function in the breakdown of
extracellular matrix proteins, have gained the status of regulatory proteases in signaling …

The work conducted using genome-wide approaches during the past several years has
invigorated the field, and represents the dawn of molecular genetics of schizophrenia. The …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by intracellular α-
synuclein (α-syn) deposition. Alterations in α-syn levels in cerebrospinal fluid (CSF) and …

Genetic variability in the promoter and 3′ region of the SNCA gene coding α‐synuclein
modulates the risk to develop sporadic Parkinson's disease (PD). Whether this is mediated …

Objective: α-Synuclein gene (SNCA) multiplication was found in familial Parkinson disease
(PD). We examined SNCA multiplication in patients with familial and sporadic PD and …