Cardiovascular comorbidity in rheumatic diseases

MT Nurmohamed, M Heslinga, GD Kitas - Nature Reviews …, 2015 - nature.com
Patients with rheumatoid arthritis (RA) and other inflammatory joint diseases (IJDs) have an
increased risk of premature death compared with the general population, mainly because of …

[HTML][HTML] Cardiovascular risk assessment in patients with rheumatoid arthritis: The relevance of clinical, genetic and serological markers

R López-Mejías, S Castañeda… - Autoimmunity …, 2016 - Elsevier
Cardiovascular disease (CV) is the most common cause of premature mortality in patients
with rheumatoid arthritis (RA). This is the result of an accelerated atherosclerotic process …

The role of osteoprotegerin in the crosstalk between vessels and bone: Its potential utility as a marker of cardiometabolic diseases

L Rochette, A Meloux, E Rigal, M Zeller, Y Cottin… - Pharmacology & …, 2018 - Elsevier
Among the numerous molecules that are being studied for their potential utility as
biomarkers of cardiovascular diseases, much interest has been shown in the superfamily of …

[HTML][HTML] Organokines in rheumatoid arthritis: A critical review

LF Laurindo, MC de Maio, SM Barbalho… - International Journal of …, 2022 - mdpi.com
Rheumatoid arthritis (RA) is a systemic autoimmune disease that primarily affects the joints.
Organokines can produce beneficial or harmful effects in this condition. Among RA patients …

[HTML][HTML] Utility of a novel inflammatory marker, GlycA, for assessment of rheumatoid arthritis disease activity and coronary atherosclerosis

MJ Ormseth, CP Chung, AM Oeser… - Arthritis research & …, 2015 - Springer
Introduction GlycA is a novel inflammatory biomarker measured using nuclear magnetic
resonance (NMR). Its NMR signal primarily represents glycosylated acute phase proteins …

Impact of obesity on autoimmune arthritis and its cardiovascular complications

K Van Raemdonck, S Umar, Z Szekanecz… - Autoimmunity …, 2018 - Elsevier
Obesity can instigate and sustain a systemic low-grade inflammatory environment that can
amplify autoimmune disorders and their associated comorbidities. Metabolic changes and …

Anti-citrullinated peptide antibodies and their value for predicting responses to biologic agents: a review

E Martin-Mola, A Balsa, R García-Vicuna… - Rheumatology …, 2016 - Springer
Anti-citrullinated peptide antibodies (ACPAs) play an important pathogenic role both at the
onset and during the disease course. These antibodies precede the clinical appearance of …

[HTML][HTML] Endothelial dysfunction in rheumatoid arthritis: mechanistic insights and correlation with circulating markers of systemic inflammation

P Totoson, K Maguin-Gaté, M Nappey, D Wendling… - PloS one, 2016 - journals.plos.org
Objectives To determine mechanisms involved in endothelial dysfunction (ED) during the
course of arthritis and to investigate the link between cytokines, chemokines and …

[HTML][HTML] Expression of osteoprotegerin and its ligands, RANKL and TRAIL, in rheumatoid arthritis

S Remuzgo-Martínez, F Genre, R López-Mejías… - Scientific reports, 2016 - nature.com
Osteoprotegerin (OPG), receptor activator of nuclear factor-ΚB ligand (RANKL) and tumor
necrosis factor-related apoptosis-inducing ligand (TRAIL) have been involved in rheumatoid …

[HTML][HTML] Beyond antibodies: B cells and the OPG/RANK-RANKL pathway in health, non-HIV disease and HIV-induced bone loss

K Titanji - Frontiers in Immunology, 2017 - frontiersin.org
HIV infection leads to severe B cell dysfunction, which manifests as impaired humoral
immune response to infection and vaccinations and is not completely reversed by otherwise …