Plant extracts and betulin from Ligaria cuneifolia inhibit P-glycoprotein function in leukemia cells
J Laiolo, CL Barbieri, MB Joray, PA Lanza… - Food and Chemical …, 2021 - Elsevier
Overexpression of P-glycoprotein (P-gp), which is linked to multidrug resistance (MDR), is
one of the underlying obstacles to the success of chemotherapy as it reduces the efficacy of …
one of the underlying obstacles to the success of chemotherapy as it reduces the efficacy of …
Determination of the Cut-off Value for Imatinib Plasma Levels Linked to Occurrence of Bone Pain in CML Patients
MS Hamza, SA Shouman, R Abdelfattah… - Drug Design …, 2023 - Taylor & Francis
Background Imatinib is used to treat chronic myelogenous leukemia (CML). Variations in
imatinib pharmacokinetics have been linked to genetic variations. That has an impact on …
imatinib pharmacokinetics have been linked to genetic variations. That has an impact on …
Anti-Cancer Effects of Oxygen-Atom-Modified Derivatives of Wasabi Components on Human Leukemia Cells
JF Lin, CW Chi, YC Huang, TH Tsai… - International Journal of …, 2023 - mdpi.com
1-Isothiocyanato-6-(methylsulfinyl)-hexanate (6-MITC) is a natural compound found in
Wasabia japonica. The synthetic derivatives 1-Isothiocyanato-6-(methylsulfenyl)-hexane …
Wasabia japonica. The synthetic derivatives 1-Isothiocyanato-6-(methylsulfenyl)-hexane …
Beyond Bone Mineral Density: The Impact of Childhood Cancer and Its Treatment on Bone Structure and Strength
The spectrum of bone morbidity in childhood cancer survivors (CCS) is broad and extends
beyond “low bone mineral density” to structural damage including fracture-induced vertebral …
beyond “low bone mineral density” to structural damage including fracture-induced vertebral …
Prenylation-dependent Ras inhibition by pamidronate inhibits pediatric acute myeloid leukemia stem and differentiated cell growth and survival
C Wang, X Liu, R He, J Li, R Pan - Biochemical and Biophysical Research …, 2019 - Elsevier
The clinical management of pediatric acute myeloid leukemia (AML) is still challenging and
identification of drugs that can enhance the efficacy of standard of care is a potential …
identification of drugs that can enhance the efficacy of standard of care is a potential …
Evolución de la densidad mineral ósea y prevalencia de litiasis renal en pacientes adultos diagnosticados de hipercalciuria idiopática en la infancia
G Pérez Suarez - 2021 - riull.ull.es
La hipercalciuria idiopática (HI) es la anomalía metabólica más frecuente presente en
pacientes, tanto en niños como adultos, con litiasis de repetición y se asocia a un balance …
pacientes, tanto en niños como adultos, con litiasis de repetición y se asocia a un balance …