Osteoarthritis (OA) is one of the most debilitating diseases and is associated with a high
personal and socioeconomic burden. So far, there is no therapy available that effectively …

There is now general agreement that osteoarthritis (OA) involves all structures in the affected
joint, culminating in the degradation of the articular cartilage. It is appropriate to focus …

Abstract Treatment of articular cartilage injuries especially osteochondral tissue requires
intervention of bioengineered scaffold. In this study, we investigated the potential of the …

Scaffolds with aligned pores are being explored in musculoskeletal tissue engineering due
to their inherent structural anisotropy. However, influence of their structure on mechanical …

Trail runners are exposed to a high number of shocks, including high-intensity shocks on
downhill sections leading to greater risk of osseous overuse injury. The type of foot strike …

Background Despite it being known that subchondral bone affects the viscoelasticity of
cartilage, there has been little research into the mechanical properties of osteochondral …

Abstract Purpose of Review This review synthesizes recent advancements in understanding
subchondral bone (SCB) biomechanics using computed tomography (CT) and micro …

Subchondral bone structure has been observed to change in osteoarthritis (OA). However, it
remains unclear how the early-stage OA changes affect the mechanics (stresses and …

Due to the limited self-healing ability of natural cartilage, several tissue engineering
strategies have been explored to develop functional replacements. Still, most of these …

Osteochondrosis arises as a result of focal failure of the blood supply to growth cartilage.
The current aim was to examine the pathogenesis of pseudocysts and true cysts in …