G protein-coupled dopamine receptors (D1, D2, D3, D4, and D5) mediate all of the
physiological functions of the catecholaminergic neurotransmitter dopamine, ranging from …

Mouse models that recapitulate the full phenotypic spectrum of a psychiatric disorder, such
as schizophrenia, are impossible. However, a more piecemeal recreation of phenotypic …

The serine/threonine kinase Akt is a downstream target of dopamine receptor signaling that
is inhibited/dephosphorylated in response to direct and indirect dopamine receptor agonists …

Many of the individual differences in cognition, motivation, and learning—and the disruption
of these processes in neurological conditions—are influenced by genetic factors. We …

Neuregulin-1 (NRG1) has been identified as a candidate susceptibility gene for
schizophrenia. In the present study the functional role of the NRG1 gene, as it relates to …

Dopamine D 3 receptor antagonists exert pro-cognitive effects in both rodents and primates.
Accordingly, this study compared the roles of dopamine D 3 vs D 2 receptors in social …

Almost 20 years ago, the gene underlying fatal familial insomnia was discovered, and first
suggested the concept that a single gene can regulate sleep. In the two decades since …

Dieses Buch vermittelt einen kompetenten und fächerübergreifenden Überblick über das
aktuelle Wissen auf dem Gebiet der Parkinson-Krankheit. Es ist im deutschsprachigen …

This book first reviews the case that brain oscillations not only are important for cognition, as
long suspected, but also play a part in the expression of signs and symptoms of …

A wealth of evidence indicates that schizophrenia is heritable. However, the genetic
mechanisms involved are poorly understood. Furthermore, it may be that genes conferring …