Enteric nervous system development: A crest cell's journey from neural tube to colon
N Nagy, AM Goldstein - Seminars in cell & developmental biology, 2017 - Elsevier
The enteric nervous system (ENS) is comprised of a network of neurons and glial cells that
are responsible for coordinating many aspects of gastrointestinal (GI) function. These cells …
are responsible for coordinating many aspects of gastrointestinal (GI) function. These cells …
Enteric nervous system development: migration, differentiation, and disease
JI Lake, RO Heuckeroth - American Journal of Physiology …, 2013 - journals.physiology.org
The enteric nervous system (ENS) provides the intrinsic innervation of the bowel and is the
most neurochemically diverse branch of the peripheral nervous system, consisting of two …
most neurochemically diverse branch of the peripheral nervous system, consisting of two …
[HTML][HTML] Spatiotemporal analysis of human intestinal development at single-cell resolution
D Fawkner-Corbett, A Antanaviciute, K Parikh… - Cell, 2021 - cell.com
Development of the human intestine is not well understood. Here, we link single-cell RNA
sequencing and spatial transcriptomics to characterize intestinal morphogenesis through …
sequencing and spatial transcriptomics to characterize intestinal morphogenesis through …
Manifold interpolating optimal-transport flows for trajectory inference
We present a method called Manifold Interpolating Optimal-Transport Flow (MIOFlow) that
learns stochastic, continuous population dynamics from static snapshot samples taken at …
learns stochastic, continuous population dynamics from static snapshot samples taken at …
Regulatory logic underlying diversification of the neural crest
ML Martik, ME Bronner - Trends in Genetics, 2017 - cell.com
The neural crest is a transient, multipotent population of cells that arises at the border of the
developing nervous system. After closure of the neural tube, these cells undergo an …
developing nervous system. After closure of the neural tube, these cells undergo an …
[HTML][HTML] scRNA-Seq reveals new enteric nervous system roles for GDNF, NRTN, and TBX3
CM Wright, S Schneider, KM Smith-Edwards… - Cellular and molecular …, 2021 - Elsevier
Background and Aims Bowel function requires coordinated activity of diverse enteric neuron
subtypes. Our aim was to define gene expression in these neuron subtypes to facilitate …
subtypes. Our aim was to define gene expression in these neuron subtypes to facilitate …
Development and developmental disorders of the enteric nervous system
F Obermayr, R Hotta, H Enomoto… - Nature reviews …, 2013 - nature.com
The enteric nervous system (ENS) arises from neural crest-derived cells that migrate into
and along the gut, leading to the formation of a complex network of neurons and glial cells …
and along the gut, leading to the formation of a complex network of neurons and glial cells …
[HTML][HTML] Building a second brain in the bowel
M Avetisyan, EM Schill… - The Journal of clinical …, 2015 - Am Soc Clin Investig
The enteric nervous system (ENS) is sometimes called the “second brain” because of the
diversity of neuronal cell types and complex, integrated circuits that permit the ENS to …
diversity of neuronal cell types and complex, integrated circuits that permit the ENS to …
Muscularis macrophage development in the absence of an enteric nervous system
M Avetisyan, JE Rood… - Proceedings of the …, 2018 - National Acad Sciences
The nervous system of the bowel regulates the inflammatory phenotype of tissue resident
muscularis macrophages (MM), and in adult mice, enteric neurons are the main local source …
muscularis macrophages (MM), and in adult mice, enteric neurons are the main local source …
[HTML][HTML] Regional cytoarchitecture of the adult and developing mouse enteric nervous system
The organization and cellular composition of tissues are key determinants of their biological
function. In the mammalian gastrointestinal (GI) tract, the enteric nervous system (ENS) …
function. In the mammalian gastrointestinal (GI) tract, the enteric nervous system (ENS) …