Inflammatory bowel diseases (IBD) are a group of chronic, incurable diseases of the
digestive tract, the etiology of which remains unclear to this day. IBD result in significant …

Ulcerative colitis (UC), a chronic inflammatory disease affecting the colon, has a rising
incidence worldwide. The known pathogenesis is multifactorial and involves genetic …

Zanthoxylum bungeanum, which belongs to the Zanthoxylum genus of the Rutaceae family,
is now wildly distributed in most parts of China and some Southeast Asian countries. The …

Background Telmisartan, a potent angiotensin II type-1 receptor blocker as well as partial
PPAR–gamma agonist, has emerged as a versatile therapeutic agent with diverse …

Background Preclinical data demonstrate that activation of the renin–angiotensin system
(RAS) contributes to mucosal inflammation, and RAS inhibition by angiotensin-converting …

Heart failure is typically related to aging as there is a definite relationship between age‐
related changes in the heart and the pathogenesis of heart failure. We have previously …

Introduction The renin-angiotensin system (RAS) is an important homeostatic pathway, with
emerging evidence for the impact of its components on inflammation and fibrosis in …

Significance: Reactive oxygen species (ROS) are essential in maintaining normal intestinal
physiology. Inflammatory bowel disease (IBD) is a relapsing chronic inflammatory disease of …

Taurocholate is a natural conjugated bile acid. The aim of this study was to evaluate the anti-
inflammatory effect of taurocholate in TNBS-induced ulcerative colitis in mice. The colitis …

Inflammatory bowel disease (IBD) is defined by the chronic inflammation of the digestive
tract. Ulcerative colitis is one of the most prevalent chronic IBDs. The increase in the …