Metabolic reconstruction identifies strain‐specific regulation of virulence in Toxoplasma gondii

C Song, MA Chiasson, N Nursimulu… - Molecular systems …, 2013 - embopress.org
Increasingly, metabolic potential is proving to be a critical determinant governing a
pathogen's virulence as well as its capacity to expand its host range. To understand the …

Active Site Loop Dynamics of a Class IIa Fructose 1,6-Bisphosphate Aldolase from Mycobacterium tuberculosis

SD Pegan, K Rukseree, GC Capodagli, EA Baker… - Biochemistry, 2013 - ACS Publications
Class II fructose 1, 6-bisphosphate aldolases (FBAs, EC 4.1. 2.13) comprise one of two
families of aldolases. Instead of forming a Schiff base intermediate using an ε-amino group …

Evaluation of four microbial Class II fructose 1, 6-bisphosphate aldolase enzymes for use as biocatalysts

G Labbé, S de Groot, T Rasmusson, G Milojevic… - Protein expression and …, 2011 - Elsevier
Fructose 1, 6-bisphosphate (FBP) aldolase has been used as biocatalyst in the synthesis of
several pharmaceutical compounds such as monosaccharides and analogs. Is has been …

Generating Novel and Soluble Class II Fructose-1, 6-Bisphosphate Aldolase with ProteinGAN

F Tang, M Ren, X Li, Z Lin, X Yang - Catalysts, 2023 - mdpi.com
Fructose-1, 6-bisphosphate aldolase (FBA) is an important enzyme involved in central
carbon metabolism (CCM) with promising industrial applications. Artificial intelligence …

Dynamics and inhibition of class II fructose 1, 6-bisphosphate aldolase

G Labbé - 2009 - uwspace.uwaterloo.ca
It has been suggested for many decades that the essential and ubiquitous enzyme fructose
1, 6-bisphosphate aldolase (FBA) could be a good drug target against bacteria and fungi …

Análisis de la distribución de flujo metabólico para la síntesis de ácido micólico en Mycobacterium tuberculosis, aislado clínico UT205

JF Muñoz Rengifo - repositorio.unal.edu.co
En Colombia cada año se reportan más de once mil nuevos casos de tuberculosis,
indicando que esta enfermedad aún continúa siendo un serio problema para la salud. La …

[图书][B] In Vitro Evolution of Aldolases; Towards a Baylis-Hillmanase

M Swiatyj - 2012 - search.proquest.com
Abstract The fructose 1, 6-bisphosphate type I aldolase from the thermophilic organism
Thermoproteus tenax has been expressed and purified by heat treatment. The aldolase …

[引用][C] 花生AhRRF 基因的克隆与原核表达

杜照奎, 李钧敏 - 核农学报, 2015