The impact of pre-existing cross-reactive immunity on SARS-CoV-2 infection and vaccine responses
Pre-existing cross-reactive immune responses to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) proteins in infection-naive subjects have been described by …
coronavirus 2 (SARS-CoV-2) proteins in infection-naive subjects have been described by …
[HTML][HTML] Immune imprinting and next-generation coronavirus vaccines
CQ Huang, S Vishwanath, GW Carnell, ACY Chan… - Nature …, 2023 - nature.com
Vaccines based on historical virus isolates provide limited protection from continuously
evolving RNA viruses, such as influenza viruses or coronaviruses, which occasionally spill …
evolving RNA viruses, such as influenza viruses or coronaviruses, which occasionally spill …
Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting
The continuing emergence of SARS-CoV-2 variants highlights the need to update COVID-19
vaccine compositions. However, immune imprinting induced by vaccination based on the …
vaccine compositions. However, immune imprinting induced by vaccination based on the …
Previous immunity shapes immune responses to SARS-CoV-2 booster vaccination and Omicron breakthrough infection risk
L Pérez-Alós, CB Hansen… - Nature …, 2023 - nature.com
The heterogeneity of the SARS-CoV-2 immune responses has become considerably more
complex over time and diverse immune imprinting is observed in vaccinated individuals …
complex over time and diverse immune imprinting is observed in vaccinated individuals …
Long-term COVID-19 booster effectiveness by infection history and clinical vulnerability and immune imprinting: a retrospective population-based cohort study
Background Long-term effectiveness of COVID-19 mRNA boosters in populations with
different previous infection histories and clinical vulnerability profiles is inadequately …
different previous infection histories and clinical vulnerability profiles is inadequately …
Protection against reinfection with the omicron BA. 2.75 subvariant
H Chemaitelly, P Tang, P Coyle… - … England Journal of …, 2023 - Mass Medical Soc
Effect of Previous SARS-CoV-2 Infection against BA. 2.75 Infection A test-negative, case–
control study in Qatar showed that previous infection with pre-omicron strains of SARS-CoV …
control study in Qatar showed that previous infection with pre-omicron strains of SARS-CoV …
New nomenclature for mpox (monkeypox) and monkeypox virus clades
D Ulaeto, A Agafonov, J Burchfield, L Carter… - The Lancet Infectious …, 2023 - thelancet.com
The first report of mpox that led to the discovery of the global outbreak was made to WHO on
May 13, 2022. The outbreak spread to 110 countries2 and was declared a public health …
May 13, 2022. The outbreak spread to 110 countries2 and was declared a public health …
Antibody and B cell responses to SARS-CoV-2 infection and vaccination: the end of the beginning
As the COVID-19 pandemic has evolved during the past years, interactions between human
immune systems, rapidly mutating and selected SARS-CoV-2 viral variants, and effective …
immune systems, rapidly mutating and selected SARS-CoV-2 viral variants, and effective …
[HTML][HTML] Deep immunological imprinting due to the ancestral spike in the current bivalent COVID-19 vaccine
To combat the evolving SARS-CoV-2 Omicron variants, bivalent COVID-19 mRNA vaccines,
encoding both ancestral and Omicron BA. 5 spikes, have replaced monovalent vaccines in …
encoding both ancestral and Omicron BA. 5 spikes, have replaced monovalent vaccines in …
Hybrid immunity to SARS-CoV-2 arises from serological recall of IgG antibodies distinctly imprinted by infection or vaccination
We describe the molecular-level composition of polyclonal immunoglobulin G (IgG) anti-
spike antibodies from ancestral severe acute respiratory syndrome coronavirus 2 (SARS …
spike antibodies from ancestral severe acute respiratory syndrome coronavirus 2 (SARS …