Sepsis is a common complication of combat injuries and trauma, and is defined as a life-
threatening organ dysfunction caused by a dysregulated host response to infection. It is also …

Sepsis represents a life-threatening organ dysfunction due to an aberrant host response. Of
note is that majority of patients have experienced a severe immune depression during and …

Sepsis acute kidney injury (SAKI) is a common complication of sepsis, accounting for 26–
50% of all acute kidney injury (AKI). AKI is an independent risk factor for increased mortality …

Systemic infections, especially in patients with chronic diseases, may result in sepsis: an
explosive, uncoordinated immune response that can lead to multisystem organ failure with a …

Natural killer cells, one of the important types of innate immune cells, play a pivotal role in
the antiviral process in vivo. It has been shown that increasing NK cell activity may promote …

Background Natural killer (NK) cells play a major role in immune tolerance after sepsis, and
the programmed cell death 1 (PD-1) and programmed cell death ligand 1 (PD-L1) system …

Purpose Sepsis, with life-threatening organ failure, is caused by the uncontrolled host
response to infection. Immune response plays an important role in the pathophysiology of …

Sepsis is a life-threatening disease caused by a systemic infection that triggers a
dysregulated immune response. Sepsis is an important cause of death in intensive care …

The high mortality rate in septic shock patients is likely due to environmental and genetic
factors, which influence the host response to infection. Two genome-wide association …

The presence of memory T cell specific for Trypanosoma cruzi in subjects with discordant
serology for Chagas disease supports a cleared infection in these subjects. Using high …