The pharmacokinetics and metabolism of ivermectin in domestic animal species

AG Canga, AMS Prieto, MJD Liébana, NF Martínez… - The Veterinary …, 2009 - Elsevier
The pharmacokinetic properties of drugs are closely related to their pharmacological
efficacy. The kinetics of ivermectin are characterised, in general terms, by a slow absorption …

[HTML][HTML] Current therapeutic applications and pharmacokinetic modulations of ivermectin

K Sharun, TS Shyamkumar, VA Aneesha… - Veterinary …, 2019 - ncbi.nlm.nih.gov
Ivermectin is considered to be a wonder drug due to its broad-spectrum antiparasitic activity
against both ectoparasites and endoparasites (under class of endectocide) and has multiple …

Pharmacokinetic features of the antiparasitic macrocyclic lactones

QA McKellar, C Gokbulut - Current Pharmaceutical …, 2012 - ingentaconnect.com
The macrocyclic lactones have pharmacokinetic properties which enhance their use against
endo-and ectoparasites in animals and man. The most consistent physico-chemical feature …

Ivermectin: A critical review on characteristics, properties, and analytical methods

V Suvarna - Journal of AOAC International, 2023 - academic.oup.com
Background Ivermectin is one of the first, safe, broad-spectrum avermectin class of
antiparasitic agent, widely used to control parasitic growth in livestock. Ivermectin being …

The efficacy of essential oil components with ivermectin against Rhipicephalus annulatus: An in-vitro study

SM Aboelhadid, AAS Abdel-Baki, SM Ibrahium… - Veterinary …, 2024 - Elsevier
Ivermectin (Iv) is widely used to control Rhipicephalus annulatus infestations in cattle in
Egypt. However, increasing resistance to ivermectin necessitates alternative approaches …

Pharmacokinetic profile of ivermectin in cattle dung excretion, and its associated environmental hazard

C Fernandez, MS Andrés, MA Porcel… - Soil and Sediment …, 2009 - Taylor & Francis
Ivermectin is a worldwide used antiparasitic compound acting against both endo-and ecto
parasites of livestock. Ivermectin can reach the environment through the direct emission of …

Comparative pharmacokinetics of some injectable preparations containing ivermectin in dogs

G Eraslan, M Kanbur, BC Liman, Y Çam… - Food and chemical …, 2010 - Elsevier
Little is known about the kinetics of ivermectin formulations following subcutaneous
administration in dogs. The vehicle components used in production may change the …

Doramectin efficacy against Psoroptes ovis in sheep: Evaluation of pharmacological strategies

M Larroza, P Soler, C Robles, R Cabrera… - Experimental …, 2020 - Elsevier
The aims of this study were to evaluate the efficacy of two injectable formulations of
doramectin (DRM) against Psoroptes ovis in sheep infested under controlled experimental …

In Vivo Protection against Strychnine Toxicity in Mice by the Glycine Receptor Agonist Ivermectin

A Maher, R Radwan… - BioMed research …, 2014 - Wiley Online Library
The inhibitory glycine receptor, a ligand‐gated ion channel that mediates fast synaptic
inhibition in mammalian spinal cord and brainstem, is potently and selectively inhibited by …

Establishment of the HPLC fluorescence detection method for plasma trace ivermectin and its pharmacokinetics in Bactrian camel

B Hou, H Wang, N Jiang, B Haosi… - Veterinary Medicine and …, 2024 - Wiley Online Library
Background and objective Ivermectin (IVM), a widely used veterinary anthelmintic, lacks
recommended doses for Bactrian camels. This study aims to establish its pharmacokinetics …