Recent advances in the synthesis of pyrroles by multicomponent reactions

V Estévez, M Villacampa, JC Menéndez - Chemical Society Reviews, 2014 - pubs.rsc.org
Pyrrole is one of the most important one-ring heterocycles. The ready availability of suitably
substituted and functionalized pyrrole derivatives is essential for the progress of many …

Transition metal-mediated synthesis of monocyclic aromatic heterocycles

AV Gulevich, AS Dudnik, N Chernyak… - Chemical …, 2013 - ACS Publications
Transition Metal-Mediated Synthesis of Monocyclic Aromatic Heterocycles | Chemical Reviews
ACS ACS Publications C&EN CAS Find my institution Log In Chemical Reviews ACS …

Active methylenes in the synthesis of a pyrrole motif: An imperative structural unit of pharmaceuticals, natural products and optoelectronic materials

R Khajuria, S Dham, KK Kapoor - RSC advances, 2016 - pubs.rsc.org
Pyrrole is one of the most important azaheterocycles, due to its wide range of applications in
pharmaceuticals and optoelectronic materials, coupled with its utility as an intermediate in …

Part I: Nitroalkenes in the synthesis of heterocyclic compounds

AZ Halimehjani, INN Namboothiri, SE Hooshmand - RSC Advances, 2014 - pubs.rsc.org
The applications of nitroalkenes in the synthesis of three-to five-membered O, N and S-
heterocycles, including natural products are investigated in this review. These heterocyclic …

Heterogeneous Fe-MIL-101 catalysts for efficient one-pot four-component coupling synthesis of highly substituted pyrroles

J Tang, M Yang, M Yang, J Wang, W Dong… - New Journal of …, 2015 - pubs.rsc.org
Four-component coupling reactions (4CRs) of 1, 3-dicarbonyl compounds, amines,
aldehydes and nitromethane have been carried out for substituted pyrroles using iron …

Synthesis of tetra-substituted pyrroles, a potential phosphodiesterase 4B inhibitor, through nickel (II) chloride hexahydrate catalyzed one-pot four-component reaction

AT Khan, M Lal, PR Bagdi, RS Basha, P Saravanan… - Tetrahedron …, 2012 - Elsevier
A wide variety of tetra-substituted pyrrole derivatives were synthesized through one-pot four-
component condensation reaction of aromatic aldehydes, benzylamines, β-ketoesters, and …

Novel N-indolylmethyl substituted olanzapine derivatives: their design, synthesis and evaluation as PDE4B inhibitors

DR Gorja, S Mukherjee, CLT Meda… - Organic & …, 2013 - pubs.rsc.org
A new strategy for converting antipsychotic drug olanzapine into PDE4 inhibitors is
described via the design and Pd/C mediated synthesis of novel N-indolylmethyl olanzapine …

Review on synthesis of pyrrole derivatives promoted by nanoparticles

H Rostami, L Shiri - Applied Organometallic Chemistry, 2021 - Wiley Online Library
Pyrrole derivatives are a special class of heterocycle compounds that have many biological
and pharmacological activities. Also, these compounds are one important portion of natural …

Iodine catalyzed four-component reaction: a straightforward one-pot synthesis of functionalized pyrroles under metal-free conditions

GR Reddy, TR Reddy, SC Joseph, KS Reddy, M Pal - RSC advances, 2012 - pubs.rsc.org
An iodine-catalyzed four-component reaction of 1, 3-dicarbonyl compounds, amines,
aldehydes and nitroalkanes afforded polysubstituted pyrroles under a metal free condition …

Construction of a six-membered fused N-heterocyclic ring via a new 3-component reaction: synthesis of (pyrazolo) pyrimidines/pyridines

P MahesháKumar, K SivaáKumar… - Chemical …, 2012 - pubs.rsc.org
Construction of a six-membered fused N -heterocyclic ring via a new 3-component reaction:
synthesis of (pyrazolo)pyrimidines/pyridines - Chemical Communications (RSC Publishing) …