Advances in the pathogenesis of psoriasis: from keratinocyte perspective

X Zhou, Y Chen, L Cui, Y Shi, C Guo - Cell death & disease, 2022 - nature.com
Psoriasis is a complex long-lasting inflammatory skin disease with high prevalence and
associated comorbidity. It is characterized by epidermal hyperplasia and dermal infiltration …

The cytokine mediated molecular pathophysiology of psoriasis and its clinical implications

R Singh, S Koppu, PO Perche, SR Feldman - International journal of …, 2021 - mdpi.com
Psoriasis is the result of uncontrolled keratinocyte proliferation, and its pathogenesis
involves the dysregulation of the immune system. The interplay among cytokines released …

A comprehensive review of autophagy and its various roles in infectious, non-infectious, and lifestyle diseases: current knowledge and prospects for disease …

R Khandia, M Dadar, A Munjal, K Dhama, K Karthik… - Cells, 2019 - mdpi.com
Autophagy (self-eating) is a conserved cellular degradation process that plays important
roles in maintaining homeostasis and preventing nutritional, metabolic, and infection …

An update on generalized pustular psoriasis

MJ Gooderham, AS Van Voorhees… - Expert review of clinical …, 2019 - Taylor & Francis
Introduction: Generalized pustular psoriasis (GPP) is a rare, severe relapsing/remitting,
multisystem disease that can be difficult to treat. Recent clinical, histological, and genetic …

Pathophysiology of generalized pustular psoriasis

S Marrakchi, L Puig - American Journal of Clinical Dermatology, 2022 - Springer
Generalized pustular psoriasis (GPP) is a rare, severe form of pustular psoriasis
characterized by widespread, recurrent episodes of neutrophil-rich pustule formation in the …

Prevalence, comorbidities and mortality of generalized pustular psoriasis: a literature review

JC Prinz, SE Choon, CEM Griffiths… - Journal of the …, 2023 - Wiley Online Library
Generalized pustular psoriasis (GPP) is a rare auto‐inflammatory skin disease characterised
by acute episodes of sterile pustule formation. Diagnosis and treatment of the disease have …

The genetic basis of psoriasis

F Capon - International journal of molecular sciences, 2017 - mdpi.com
Psoriasis is widely regarded as a multifactorial condition which is caused by the interaction
between inherited susceptibility alleles and environmental triggers. In the last decade …

[HTML][HTML] Clinical and genetic differences between pustular psoriasis subtypes

S Twelves, A Mostafa, N Dand, E Burri, K Farkas… - Journal of allergy and …, 2019 - Elsevier
Background The term pustular psoriasis indicates a group of severe skin disorders
characterized by eruptions of neutrophil-filled pustules. The disease, which often manifests …

Generalized pustular psoriasis is a disease distinct from psoriasis vulgaris: evidence and expert opinion

H Bachelez, J Barker, AD Burden… - Expert Review of …, 2022 - Taylor & Francis
Introduction Generalized pustular psoriasis (GPP) is a rare, severe, clinically heterogeneous
disease characterized by flares of widespread, noninfectious, macroscopically visible …

Regulation and function of interleukin‐36 cytokines

EY Bassoy, JE Towne, C Gabay - Immunological reviews, 2018 - Wiley Online Library
Summary The interleukin (IL)‐36 cytokines include 3 agonists, IL‐36α, IL‐36β, and IL‐36γ
that bind to a common receptor composed of IL‐36R and IL‐1 RA cP to stimulate …