Neurotransmitters play critical roles in the developing nervous system. Among the
neurotransmitters, norepinephrine (NE) is in particular postulated to be an important …

Modelling of complex psychiatric disorders, eg, depression and schizophrenia, in animals is
a major challenge, since they are characterized by certain disturbances in functions that are …

The inability to discriminate between threat and safety is a hallmark of stress-induced
psychiatric disorders, including post-traumatic stress disorder. Dorsolateral bed nucleus of …

Abstract Changes in gene expression of the brain serotonin (5-HT) 1A receptors may be
important for the development and ameliorating depression, however identification of …

We have previously reported that chronic imipramine and electroconvulsive treatments
increase the α 1A-adrenoceptor (but not the α 1B subtype) mRNAlevel and the receptor …

To examine the effect of a central noradrenergic lesion on the reactivity of the 5-HT 1B
receptor we compared intact male rats with rats in which noradrenergic nerve terminals were …

Introduction Since little has been known about the effect of the central noradrenergic system
on the reactivity of serotonin 5-HT 3 receptors, the aim of the current study was to find out …

Abstract N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) is a highly selective
neurotoxin for noradrenergic projections originating from the locus coeruleus (LC). The …

The investigations of noradrenergic lesions and dopaminergic lesions have established
particular profiles of functional deficits and accompanying alterations of biomarkers in brain …

BACKGROUND The aim of the present study was to examine the impact of the central
noradrenergic system on the serotoninergic 5-HT3 receptor mediated analgesia in rats …