Multifactor transcriptional control of alternative oxidase induction integrates diverse environmental inputs to enable fungal virulence

Z Liu, P Basso, S Hossain, SD Liston… - Nature …, 2023 - nature.com
Metabolic flexibility enables fungi to invade challenging host environments. In Candida
albicans, a common cause of life-threatening infections in humans, an important contributor …

Alternative Oxidase: From Molecule and Function to Future Inhibitors

J Li, S Yang, Y Wu, R Wang, Y Liu, J Liu, Z Ye… - ACS …, 2024 - ACS Publications
In the respiratory chain of the majority of aerobic organisms, the enzyme alternative oxidase
(AOX) functions as the terminal oxidase and has important roles in maintaining metabolic …

Nanostructured Lipid Carriers Loaded with Lippia sidoides Essential Oil as a Strategy to Combat the Multidrug-Resistant Candida auris

I Baldim, MH Paziani, PH Grizante Barião, MRZ Kress… - Pharmaceutics, 2022 - mdpi.com
The emerging pathogen Candida auris is an emerging fungal pathogen that was associated
with nosocomial infectious outbreaks. Its worldwide incidence and the emerging multidrug …

[HTML][HTML] Alternative Oxidase–Aid or obstacle to combat the rise of fungal pathogens?

ESM Edrich, L Duvenage, CW Gourlay - Biochimica et Biophysica Acta …, 2024 - Elsevier
Fungal pathogens present a growing threat to both humans and global health security alike.
Increasing evidence of antifungal resistance in fungal populations that infect both humans …

Targeting the alternative oxidase (AOX) for human health and food security, a pharmaceutical and agrochemical target or a rescue mechanism?

M Szibor, C Schenkl, MRO Barsottini… - Biochemical …, 2022 - portlandpress.com
Some of the most threatening human diseases are due to a blockage of the mitochondrial
electron transport chain (ETC). In a variety of plants, fungi, and prokaryotes, there is a …

Production of new ent-hardwickiic acid derivatives by microbial transformation and their antifungal activity

MVS Teixeira, LM Fernandes, VS de Paula… - Fitoterapia, 2024 - Elsevier
Ent-hardwickiic acid is the major compound of Copaifera pubiflora Benth oleoresin
traditionally used in Brazilian folk medicine as an antimicrobial agent. Microbial …

Production of More Potent Anti‐Candida Labdane Diterpenes by Biotransformation Using Cunninghamella elegans

IP Sousa, MV De Sousa Teixeira… - Chemistry & …, 2022 - Wiley Online Library
Candida species are responsible for causing invasive candidiasis with high mortality rate
and their resistance to available antifungal drugs is a major clinical challenge …

[PDF][PDF] ОСНОВНЫЕ ФИЗИОЛОГО-БИОХИМИЧЕСКИЕ И МОЛЕКУЛЯРНЫЕ АСПЕКТЫ АДАПТАЦИИ К СТРЕССОВЫМ ФАКТОРАМ У ДРОЖЖЕЙ YARROWIA …

ВЮ Секова - fbras.ru
Актуальность работы. Yarrowia lipolytica–полиэкстремофильные «нестандартные»
дрожжи, имеющие большой потенциал использования во всех сферах современной …