Microbial biofilm: a review on formation, infection, antibiotic resistance, control measures, and innovative treatment

S Sharma, J Mohler, SD Mahajan, SA Schwartz… - Microorganisms, 2023 - mdpi.com
Biofilm is complex and consists of bacterial colonies that reside in an exopolysaccharide
matrix that attaches to foreign surfaces in a living organism. Biofilm frequently leads to …

Microbial biofilm: formation, architecture, antibiotic resistance, and control strategies

MA Rather, K Gupta, M Mandal - Brazilian Journal of Microbiology, 2021 - Springer
The assembly of microorganisms over a surface and their ability to develop resistance
against available antibiotics are major concerns of interest. To survive against harsh …

[HTML][HTML] Biofilms: Formation, drug resistance and alternatives to conventional approaches

R Mirghani, T Saba, H Khaliq, J Mitchell, L Do… - AIMS …, 2022 - ncbi.nlm.nih.gov
Biofilms are aggregates of bacteria, in most cases, which are resistant usually to broad-
spectrum antibiotics in their typical concentrations or even in higher doses. A trend of …

Living in the matrix: assembly and control of Vibrio cholerae biofilms

JK Teschler, D Zamorano-Sánchez, AS Utada… - Nature Reviews …, 2015 - nature.com
Nearly all bacteria form biofilms as a strategy for survival and persistence. Biofilms are
associated with biotic and abiotic surfaces and are composed of aggregates of cells that are …

Bacterial biofilm infections, their resistance to antibiotics therapy and current treatment strategies

A Singh, A Amod, P Pandey, P Bose… - Biomedical …, 2022 - iopscience.iop.org
Nearly 80% of human chronic infections are caused due to bacterial biofilm formation. This
is the most leading cause for failure of medical implants resulting in high morbidity and …

Novel strategies for the prevention and treatment of biofilm related infections

M Chen, Q Yu, H Sun - International journal of molecular sciences, 2013 - mdpi.com
Biofilm formation by human bacterial pathogens on implanted medical devices causes major
morbidity and mortality among patients, and leads to billions of dollars in healthcare cost …

Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections

S Wagner, R Sommer, S Hinsberger, C Lu… - Journal of medicinal …, 2016 - ACS Publications
Infections with Pseudomonas aeruginosa have become a concerning threat in hospital-
acquired infections and for cystic fibrosis patients. The major problem leading to high …

Agents that inhibit bacterial biofilm formation

N Rabin, Y Zheng, C Opoku-Temeng, Y Du… - Future medicinal …, 2015 - Taylor & Francis
In the biofilm form, bacteria are more resistant to various antimicrobial treatments. Bacteria in
a biofilm can also survive harsh conditions and withstand the host's immune system …

Synthetic small molecules as anti-biofilm agents in the struggle against antibiotic resistance

B Parrino, D Schillaci, I Carnevale, E Giovannetti… - European journal of …, 2019 - Elsevier
Biofilm formation significantly contributes to microbial survival in hostile environments and it
is currently considered a key virulence factor for pathogens responsible for serious chronic …

Small molecule control of bacterial biofilms

RJ Worthington, JJ Richards… - Organic & biomolecular …, 2012 - pubs.rsc.org
Bacterial biofilms are defined as a surface attached community of bacteria embedded in a
matrix of extracellular polymeric substances that they have produced. When in the biofilm …