Ischemic heart disease (IHD) is the leading cause of disability and mortality worldwide.
Reactive oxygen species (ROS) have been shown to play key roles in the progression of …

The statins have been used for 30 years to prevent coronary artery disease and stroke. Their
primary mechanism of action is the lowering of serum cholesterol through inhibiting hepatic …

With cardiovascular disease being the leading cause of morbidity and mortality worldwide,
effective and cost-efficient therapies to reduce cardiovascular risk are highly needed. Lipids …

Diabetes mellitus is associated to an increased risk of cardiovascular diseases.
Hyperglycemia is an important factor in cardiovascular damage, working through different …

Statins represent the cornerstone of pharmacotherapy for the prevention of atherosclerotic
cardiovascular disease. These medications not only reduce low-density lipoprotein …

Oxidative stress and cardiovascular disease: new insights Page 1 Address for correspondence:
Prof. Francesco Violi, I Clinica Medica, Viale del Policlinico 155, Roma, 00161, Italy, tel …

Atherosclerosis can be regarded as chronic inflammatory disease affecting the arterial wall.
Despite the recent progress in studying the pathogenesis of atherosclerosis, some of the …

Background Statin use could benefit patients with non-alcoholic fatty liver disease (NAFLD),
but the evidence is segmented and inconclusive. This multidimensional study …

Reactive oxygen species (ROS) have physiological roles as second messengers, but can
also exert detrimental modifications on DNA, proteins and lipids if resulting from enhanced …

Background The role of aspirin in primary prevention of cardiovascular disease (CVD)
remains unclear. We aimed to investigate the benefit-risk ratio of aspirin for primary …