Tubulin isotypes: emerging roles in defining cancer stem cell niche

TT Maliekal, D Dharmapal, S Sengupta - Frontiers in Immunology, 2022 - frontiersin.org
Although the role of microtubule dynamics in cancer progression is well-established, the
roles of tubulin isotypes, their cargos and their specific function in the induction and …

TUBB4B is a novel therapeutic target in non‐alcoholic fatty liver disease‐associated hepatocellular carcinoma

Z Yang, S Gao, CC Wong, W Liu, H Chen… - The Journal of …, 2023 - Wiley Online Library
Non‐alcoholic fatty liver disease‐associated hepatocellular carcinoma (NAFLD‐HCC) is an
emerging malignancy due to the rising prevalence of NAFLD. However, no drug is available …

ALDH1A1 as a marker for metastasis initiating cells: a mechanistic insight

N Datta, VP Snijesh, K Parvathy, AS Sneha… - Experimental Cell …, 2024 - Elsevier
Since metastasis accounts for the majority of cancer morbidity and mortality, attempts are
focused to block metastasis and metastasis initiating cellular programs. It is generally …

[HTML][HTML] Chronic lung inflammation and CK14+ basal cell proliferation induce persistent alveolar-bronchiolization in SARS-CoV-2-infected hamsters

C Li, N Xiao, W Song, AHC Lam, F Liu, X Cui, Z Ye… - Ebiomedicine, 2024 - thelancet.com
Background Post-acute sequalae of COVID-19 defines a wide range of ongoing symptoms
and conditions long after SARS-CoV-2 infection including respiratory diseases. The …

Comprehensive data mining reveals RTK/RAS signaling pathway as a promoter of prostate cancer lineage plasticity through transcription factors and CNV

G Wei, X Zhang, S Liu, W Hou, Z Dai - Scientific Reports, 2024 - nature.com
Prostate cancer lineage plasticity is a key driver in the transition to neuroendocrine prostate
cancer (NEPC), and the RTK/RAS signaling pathway is a well-established cancer pathway …

Two-Dimensional-PAGE Coupled with nLC-MS/MS-Based Identification of Differentially Expressed Proteins and Tumorigenic Pathways in MCF7 Breast Cancer Cells …

M Jayathirtha, T Jayaweera, D Whitham, I Sullivan… - Molecules, 2023 - mdpi.com
The identification of new cancer-associated genes/proteins, the characterization of their
expression variation, the interactomics-based assessment of differentially expressed …

R391 human dominant mutation does not affect TubB4b localization and sensory hair cells structure in zebrafish inner ear and lateral line.

W Smaili, C Pezet, S Marlin, S Ernest - Developmental Biology, 2024 - Elsevier
ABSTRACT Heterozygous R391 TUBB4B pathogenic variations are responsible for an
association of hearing loss and retinal dystrophy in human. With the goal of understanding …

[HTML][HTML] 小鼠初级精母细胞GC-2 中TUBB4B 的表达及其对NF-κB 和MAPK 信号通路的调控

刘桐佳, 王万伦, 张婷, 刘爽, 边艳超… - Journal of Southern …, 2023 - ncbi.nlm.nih.gov
小鼠初级精母细胞GC-2中TUBB4B的表达及其对NF-κB和MAPK信号通路的调控- PMC Back to
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Hindbrain boundaries as niches of neural progenitor and stem cells regulated by the extracellular matrix proteoglycan chondroitin sulphate

C Hutchings, Y Nuriel, D Lazar, A Kohl, E Muir… - …, 2024 - journals.biologists.com
The interplay between neural progenitors and stem cells (NPSCs), and their extracellular
matrix (ECM) is a crucial regulatory mechanism that determines their behavior. Nonetheless …

Expression of TUBB4B in mouse primary spermatocyte GC-2 cells and its regulatory effect on NF-κB and MAPK signaling pathway

T Liu, W Wang, T Zhang, S Liu, Y Bian… - … Fang yi ke da xue xue …, 2023 - europepmc.org
Objective To explore the interaction between Tubulin beta 4B class IVb (TUBB4B) and
Agtpbp1/cytosolic carboxypeptidase-like1 (CCP1) in mouse primary spermatocytes (GC-2 …