[HTML][HTML] Towards organoid culture without Matrigel
Organoids—cellular aggregates derived from stem or progenitor cells that recapitulate organ
function in miniature—are of growing interest in developmental biology and medicine …
function in miniature—are of growing interest in developmental biology and medicine …
Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine
Extracellular matrix is rich in biomolecules including structural proteins,
glycosaminoglycans, and small molecules that are important for the maintenance and repair …
glycosaminoglycans, and small molecules that are important for the maintenance and repair …
[HTML][HTML] Extracellular matrix hydrogel derived from decellularized tissues enables endodermal organoid culture
Organoids have extensive therapeutic potential and are increasingly opening up new
avenues within regenerative medicine. However, their clinical application is greatly limited …
avenues within regenerative medicine. However, their clinical application is greatly limited …
[HTML][HTML] Microtechnology-based methods for organoid models
V Velasco, SA Shariati, R Esfandyarpour - Microsystems & …, 2020 - nature.com
Innovations in biomaterials and stem cell technology have allowed for the emergence of
novel three-dimensional (3D) tissue-like structures known as organoids and spheroids. As a …
novel three-dimensional (3D) tissue-like structures known as organoids and spheroids. As a …
[HTML][HTML] Advances in hydrogel-based vascularized tissues for tissue repair and drug screening
The construction of biomimetic vasculatures within the artificial tissue models or organs is
highly required for conveying nutrients, oxygen, and waste products, for improving the …
highly required for conveying nutrients, oxygen, and waste products, for improving the …
[HTML][HTML] Research progress in decellularized extracellular matrix-derived hydrogels
W Zhang, A Du, S Liu, M Lv, S Chen - Regenerative therapy, 2021 - Elsevier
Decellularized extracellular matrix (dECM) is widely used in regenerative medicine as a
scaffold material due to its unique biological activity and good biocompatibility. Hydrogel is a …
scaffold material due to its unique biological activity and good biocompatibility. Hydrogel is a …
[HTML][HTML] Promising applications of tumor spheroids and organoids for personalized medicine
Simple Summary Presently, the investigation of the tumor is carried out using different
models. One of the promising areas is the creation of 3D tumor models, such as spheroids …
models. One of the promising areas is the creation of 3D tumor models, such as spheroids …
[HTML][HTML] Mechano-modulatory synthetic niches for liver organoid derivation
G Sorrentino, S Rezakhani, E Yildiz, S Nuciforo… - Nature …, 2020 - nature.com
The recent demonstration that primary cells from the liver can be expanded in vitro as
organoids holds enormous promise for regenerative medicine and disease modelling. The …
organoids holds enormous promise for regenerative medicine and disease modelling. The …
Decellularized extracellular matrix for remodeling bioengineering organoid's microenvironment
L Zhu, J Yuhan, H Yu, B Zhang, K Huang, L Zhu - Small, 2023 - Wiley Online Library
Over the past decade, stem cell‐and tumor‐derived organoids are the most promising
models in developmental biology and disease modeling, respectively. The matrix is one of …
models in developmental biology and disease modeling, respectively. The matrix is one of …
Engineered biomimetic hydrogels for organoids
Y Li, Q Saiding, Z Wang, W Cui - Progress in Materials Science, 2023 - Elsevier
Organoids, intricate three-dimensional tissue assemblies derived from either pluripotent or
adult stem cells cultured under laboratory conditions, emerge as a captivating model and …
adult stem cells cultured under laboratory conditions, emerge as a captivating model and …