The field of cardiac tissue engineering has made significant strides over the last few
decades, highlighted by the development of human cell derived constructs that have shown …

An item is chiral if it cannot be superimposed on its mirror image. Most biological molecules
are chiral. The homochirality of amino acids ensures that proteins are chiral, which is …

TGF-β family ligands function in inducing and patterning many tissues of the early vertebrate
embryonic body plan. Nodal signaling is essential for the specification of mesendodermal …

Vertebrates exhibit striking left–right (L–R) asymmetries in the structure and position of the
internal organs. Symmetry is broken by motile cilia-generated asymmetric fluid flow …

Mechanotransduction refers to the conversion of mechanical forces into biochemical or
electrical signals that initiate structural and functional remodeling in cells and tissues. The …

Extensive studies have shown how bilateral symmetry of the vertebrate embryo is broken
during early development, resulting in a molecular left-right bias in the mesoderm. However …

The contribution of endocardial cells (EdCs) to the hematopoietic lineages has been
strongly debated. Here, we provide evidence that in zebrafish, the endocardium gives rise to …

Most animals show external bilateral symmetry, which hinders the observation of multiple
internal left–right (L/R) asymmetries that are fundamental to organ packaging and function …

Hemodynamic forces are fundamental to development. Indeed, much of cardiovascular
morphogenesis reflects a two-way interaction between mechanical forces and the gene …

X-ray free electron lasers (FEL) coupled with optical lasers have opened unprecedented
opportunities for studying ultrafast dynamics in matter. The major challenge in pump-probe …