Artificial intelligence aids in development of nanomedicines for cancer management
P Tan, X Chen, H Zhang, Q Wei, K Luo - Seminars in cancer biology, 2023 - Elsevier
Over the last decade, the nanomedicine has experienced unprecedented development in
diagnosis and management of diseases. A number of nanomedicines have been approved …
diagnosis and management of diseases. A number of nanomedicines have been approved …
High-throughput sequencing technologies
JA Reuter, DV Spacek, MP Snyder - Molecular cell, 2015 - cell.com
The human genome sequence has profoundly altered our understanding of biology, human
diversity, and disease. The path from the first draft sequence to our nascent era of personal …
diversity, and disease. The path from the first draft sequence to our nascent era of personal …
Advancements in next-generation sequencing
The term next-generation sequencing is almost a decade old, but it remains the colloquial
way to describe highly parallel or high-output sequencing methods that produce data at or …
way to describe highly parallel or high-output sequencing methods that produce data at or …
Translation elongation and recoding in eukaryotes
In this review, we highlight the current understanding of translation elongation and recoding
in eukaryotes. In addition to providing an overview of the process, recent advances in our …
in eukaryotes. In addition to providing an overview of the process, recent advances in our …
Next-generation sequencing platforms
ER Mardis - Annual review of analytical chemistry, 2013 - annualreviews.org
Automated DNA sequencing instruments embody an elegant interplay among chemistry,
engineering, software, and molecular biology and have built upon Sanger's founding …
engineering, software, and molecular biology and have built upon Sanger's founding …
Synonymous but not the same: the causes and consequences of codon bias
JB Plotkin, G Kudla - Nature Reviews Genetics, 2011 - nature.com
Despite their name, synonymous mutations have significant consequences for cellular
processes in all taxa. As a result, an understanding of codon bias is central to fields as …
processes in all taxa. As a result, an understanding of codon bias is central to fields as …
Reduction of translating ribosomes enables Escherichia coli to maintain elongation rates during slow growth
X Dai, M Zhu, M Warren, R Balakrishnan… - Nature …, 2016 - nature.com
Bacteria growing under different conditions experience a broad range of demand on the rate
of protein synthesis, which profoundly affects cellular resource allocation. During fast growth …
of protein synthesis, which profoundly affects cellular resource allocation. During fast growth …
Fluorescence enhancement at docking sites of DNA-directed self-assembled nanoantennas
GP Acuna, FM Möller, P Holzmeister, S Beater… - Science, 2012 - science.org
We introduce self-assembled nanoantennas to enhance the fluorescence intensity in a
plasmonic hotspot of zeptoliter volume. The nanoantennas are prepared by attaching one or …
plasmonic hotspot of zeptoliter volume. The nanoantennas are prepared by attaching one or …
A window into third-generation sequencing
EE Schadt, S Turner, A Kasarskis - Human molecular genetics, 2010 - academic.oup.com
First-and second-generation sequencing technologies have led the way in revolutionizing
the field of genomics and beyond, motivating an astonishing number of scientific advances …
the field of genomics and beyond, motivating an astonishing number of scientific advances …
The elongation, termination, and recycling phases of translation in eukaryotes
This work summarizes our current understanding of the elongation and termination/recycling
phases of eukaryotic protein synthesis. We focus here on recent advances in the field. In …
phases of eukaryotic protein synthesis. We focus here on recent advances in the field. In …