On the characteristics of functional magnetic resonance imaging of the brain

S Ogawa, RS Menon, SG Kim… - Annual review of …, 1998 - annualreviews.org
▪ Abstract In this review we discuss various recent topics that characterize functional
magnetic resonance imaging (fMRI). These topics include a brief description of MRI image …

Separating vascular and neuronal effects of age on fMRI BOLD signals

KA Tsvetanov, RNA Henson… - … Transactions of the …, 2021 - royalsocietypublishing.org
Accurate identification of brain function is necessary to understand the neurobiology of
cognitive ageing, and thereby promote well-being across the lifespan. A common tool used …

Mapping cerebrovascular reactivity using blood oxygen level-dependent MRI in patients with arterial steno-occlusive disease: comparison with arterial spin labeling …

DM Mandell, JS Han, J Poublanc, AP Crawley… - Stroke, 2008 - Am Heart Assoc
Background and Purpose—Blood oxygen level-dependent MRI (BOLD MRI) of hypercapnia-
induced changes in cerebral blood flow is an emerging technique for mapping …

Regional differences in the CBF and BOLD responses to hypercapnia: a combined PET and fMRI study

E Rostrup, I Law, M Blinkenberg, HBW Larsson… - Neuroimage, 2000 - Elsevier
Previous fMRI studies of the cerebrovascular response to hypercapnia have shown signal
change in cerebral gray matter, but not in white matter. Therefore, the objective of the …

Assessment of cerebrovascular reactivity with functional magnetic resonance imaging: comparison of CO2 and breath holding

A Kastrup, G Krüger, T Neumann-Haefelin… - Magnetic resonance …, 2001 - Elsevier
Cerebral blood flow (CBF) and oxygenation changes following both a simple breath holding
test (BHT) and a CO2 challenge can be detected with functional magnetic resonance …

Determination of relative CMRO2 from CBF and BOLD changes: Significant increase of oxygen consumption rate during visual stimulation

SG Kim, E Rostrup, HBW Larsson… - … in Medicine: An …, 1999 - Wiley Online Library
The blood oxygenation level‐dependent (BOLD) effect in functional magnetic resonance
imaging depends on at least partial uncoupling between cerebral blood flow (CBF) and …

Comparison of Cerebral Vascular Reactivity Measures Obtained Using Breath-Holding and CO2 Inhalation

FB Tancredi, RD Hoge - Journal of Cerebral Blood Flow & …, 2013 - journals.sagepub.com
Stimulation of cerebral vasculature using hypercapnia has been widely used to study
cerebral vascular reactivity (CVR), which can be expressed as the quantitative change in …

Early fMRI responses to somatosensory and optogenetic stimulation reflect neural information flow

WB Jung, GH Im, H Jiang… - Proceedings of the …, 2021 - National Acad Sciences
Blood oxygenation level–dependent (BOLD) functional magnetic resonance imaging (fMRI)
has been widely used to localize brain functions. To further advance understanding of brain …

Variability of physiological brain perfusion in healthy subjects–A systematic review of modifiers. Considerations for multi-center ASL studies

P Clement, HJ Mutsaerts, L Václavů… - Journal of Cerebral …, 2018 - journals.sagepub.com
Quantitative measurements of brain perfusion are influenced by perfusion-modifiers.
Standardization of measurement conditions and correction for important modifiers is …

A hypercapnia‐based normalization method for improved spatial localization of human brain activation with fMRI

PA Bandettini, EC Wong - NMR in Biomedicine, 1997 - Wiley Online Library
The utility of functional magnetic resonance imaging (fMRI) as a brain mapping tool is
directly related to the degree to which the relationship between MRI signal changes and …