Juvenile idiopathic arthritis (JIA) is an umbrella term for arthritis of unknown origin, lasting
for> 6 weeks with onset before 16 years of age. JIA is the most common chronic …

Abstract In 1973, IL-6 was identified as a soluble factor that is secreted by T cells and is
important for antibody production by B cells. Since its discovery more than 40 years ago, the …

Anemia of inflammation (AI), also known as anemia of chronic disease (ACD), is regarded
as the most frequent anemia in hospitalized and chronically ill patients. It is prevalent in …

Anemia of Inflammation Anemia of inflammation is a common normocytic, normochromic
anemia associated with systemic inflammation that increases the level of hepcidin and …

Background Systemic juvenile idiopathic arthritis (JIA) is the most severe subtype of JIA;
treatment options are limited. Interleukin-6 plays a pathogenic role in systemic JIA. Methods …

Anemia of inflammation (AI, formerly also called anemia of chronic disease or anemia of
chronic disorders) is usually a mild to moderately severe anemia (hemoglobin rarely lower …

New therapeutic strategies have emerged along with our understanding that disturbances of
iron homeostasis, impaired proliferation of erythroid progenitor cells, and blunted …

Juvenile idiopathic arthritis is a broad term that describes a clinically heterogeneous group
of arthritides of unknown cause, which begin before 16 years of age. This term …

Serum ferritin level is one of the most commonly requested investigations in both primary
and secondary care. Whilst low serum ferritin levels invariably indicate reduced iron stores …

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