Association between maternal periodontitis and development of systematic diseases in offspring

A Starzyńska, P Wychowański, M Nowak… - International Journal of …, 2022 - mdpi.com
Periodontal disease (PD) is one of the most common oral conditions affecting both youths
and adults. There are some research works suggesting a high incidence of PD in pregnant …

[HTML][HTML] Relationship among periodontal disease, insulin resistance, salivary cortisol, and stress levels during pregnancy

APCG Seraphim, FY Chiba, RF Pereira… - Brazilian dental …, 2016 - SciELO Brasil
Pregnancy is a period involving important metabolic changes that enable the maintenance
of the mother's health and development of the fetus. This study aimed to assess the …

[HTML][HTML] Melatonin promotes reduction in TNF levels and improves the lipid profile and insulin sensitivity in pinealectomized rats with periodontal disease

RM Dos Santos, F Marani, FY Chiba, MSLC Mattera… - Life sciences, 2018 - Elsevier
Aim This study aimed to investigate the effects of melatonin (ME) on insulin resistance (IR)
and signaling (IS), proinflammatory cytokine levels, and lipid profiles in pinealectomyzed …

Association between periodontal condition and the development of type 2 diabetes mellitus—Results from a 15‐year follow‐up study

V Myllymäki, T Saxlin, M Knuuttila… - Journal of clinical …, 2018 - Wiley Online Library
Aim To study whether periodontal condition is associated with the development of type 2
diabetes mellitus (T2 DM). Materials and Methods A population‐based follow‐up study was …

Maternal apical periodontitis is associated with insulin resistance in adult offspring

TVS Tsosura, FY Chiba, M Mattera… - International …, 2019 - Wiley Online Library
Aim To investigate the plasma concentrations of glucose, insulin and tumour necrosis factor‐
α (TNF‐α) of rats with maternal apical periodontitis (AP) and to explore the effect of maternal …

Effect of maternal periodontitis on GLUT4 and inflammatory pathway in adult offspring

MSLC Mattera, FY Chiba, FL Lopes… - Journal of …, 2019 - Wiley Online Library
Background Maternal periodontal disease leads to low birth weight (LBW), insulin resistance
(IR), increased TNF‐α levels, and alterations in insulin signaling in adult offspring. TNF‐α …

Maternal apical periodontitis increases insulin resistance and modulates the antioxidant defense system in the gastrocnemius muscle of adult offspring

TVS Tsosura, RM Dos Santos, AHC Neto, FY Chiba… - Journal of …, 2021 - Elsevier
Introduction Maternal apical periodontitis (AP) is associated with insulin resistance (IR) in
adult offspring. Oxidative stress has been linked to IR. This study investigated insulin …

Maternal periodontitis decreases plasma membrane GLUT4 content in skeletal muscle of adult offspring

MSLC Mattera, FY Chiba, MSO da Mota, RF Pereira… - Life sciences, 2016 - Elsevier
Aims The fetal programming hypothesis suggests that intrauterine stimuli can induce
metabolic changes in offspring, increasing the disease risk in adulthood. Periodontal …

Effect of maternal apical periodontitis on the final step of insulin signalling and inflammatory pathway in the adult male offspring of rats

TVS Tsosura, MSLC Mattera, FY Chiba… - International …, 2021 - Wiley Online Library
Aim To evaluate the final step of insulin signalling, inflammatory pathway (related to the
inhibition of insulin signalling), peroxisome proliferator‐activated receptor‐gamma …

慢性牙周炎与2 型糖尿病的关系研究进展

陈汀兰, 宋忠臣, 束蓉 - 口腔医学杂志, 2015 - stomatology.cn
慢性牙周炎(chronic periodontitis, CP) 与糖尿病(diabetes mellitus, DM) 关系密切,
其相互影响是近年来牙周医学研究的热点. DM 是CP 的危险因素之一, 可通过多种机制促进CP …