The need for pediatric formulations to treat children with HIV

AF Schlatter, AR Deathe… - AIDS Research and …, 2016 - Wiley Online Library
Over 3.2 million children worldwide are infected with HIV, but only 24% of these children
receive antiretroviral therapy (ART). ART adherence among children is a crucial part of …

Cost‐effectiveness of routine viral load monitoring in low‐and middle‐income countries: a systematic review

RV Barnabas, P Revill, N Tan… - Journal of the …, 2017 - Wiley Online Library
Introduction Routine viral load monitoring for HIV‐1 management of persons on antiretroviral
therapy (ART) has been recommended by the World Health Organization (WHO) to identify …

Cost-effective interventions for breast cancer, cervical cancer, and colorectal cancer: new results from WHO-CHOICE

AH Ralaidovy, C Gopalappa, A Ilbawi… - Cost Effectiveness and …, 2018 - Springer
Background Following the adoption of the Global Action Plan for the Prevention and Control
of NCDs 2013–2020, an update to the Appendix 3 of the action plan was requested by …

Clinical impact and cost-effectiveness of diagnosing HIV infection during early infancy in South Africa: test timing and frequency

JA Francke, M Penazzato, T Hou… - The Journal of …, 2016 - academic.oup.com
Background. Diagnosis of human immunodeficiency virus (HIV) infection during early
infancy (commonly known as “early infant HIV diagnosis” EID) followed by prompt initiation …

Incorporating the HIV Infant Tracking System into standard-of-care early infant diagnosis of HIV services in Kenya: a cost-effectiveness analysis of the HITSystem …

S Finocchario-Kessler, K Goggin, C Wexler… - The Lancet Global …, 2023 - thelancet.com
Summary Background The HITSystem efficacy trial showed significant improvements in
early infant diagnosis retention, return and notification of infant test results, and earlier …

The value of confirmatory testing in early infant HIV diagnosis programmes in South Africa: a cost-effectiveness analysis

L Dunning, JA Francke, D Mallampati… - PLoS …, 2017 - journals.plos.org
Background The specificity of nucleic acid amplification tests (NAATs) used for early infant
diagnosis (EID) of HIV infection is< 100%, leading some HIV-uninfected infants to be …

Orphans and vulnerable children affected by human immunodeficiency virus in sub-Saharan Africa

M Bryant, J Beard - Pediatric Clinics, 2016 - pediatric.theclinics.com
Globally, 39 million people have died since the beginning of the human immunodeficiency
virus (HIV) pandemic. 1 An estimated 17.8 million children have lost 1 or both parents to …

Strengthening existing laboratory-based systems vs. investing in point-of-care assays for early infant diagnosis of HIV: a model-based cost-effectiveness analysis

NC McCann, J Cohn, C Flanagan… - JAIDS Journal of …, 2020 - journals.lww.com
Background: To improve early infant HIV diagnosis (EID) programs, options include
replacing laboratory-based tests with point-of-care (POC) assays or investing in …

Partners-based HIV treatment for seroconcordant couples attending antenatal and postnatal care in rural Mozambique: a cluster randomized trial protocol

CM Audet, E Graves, E Barreto, C De Schacht… - Contemporary clinical …, 2018 - Elsevier
Background In resource-limited rural settings, scale-up of services to eliminate mother-to-
child transmission of HIV has not been as effective as in better resourced urban settings. In …

Evaluation of treatment response, drug resistance and HIV-1 variability among adolescents on first-and second-line antiretroviral therapy: a study protocol for a …

J Fokam, MM Santoro, D Takou, AE Njom-Nlend… - BMC pediatrics, 2019 - Springer
Abstract Background Sub-Saharan Africa (SSA) alone has nine out of every 10 children
living with HIV globally and monitoring in this setting remains suboptimal, even as these …