Lipid droplets in the nervous system

I Ralhan, CL Chang, J Lippincott-Schwartz… - Journal of Cell …, 2021 - rupress.org
Lipid droplets are dynamic intracellular lipid storage organelles that respond to the
physiological state of cells. In addition to controlling cell metabolism, they play a protective …

Lipid droplets and lipid mediators in viral infection and immunity

EA Monson, AM Trenerry, JL Laws… - FEMS microbiology …, 2021 - academic.oup.com
Lipid droplets (LDs) contribute to key pathways important for the physiology and
pathophysiology of cells. In a homeostatic view, LDs regulate the storage of neutral lipids …

Lipid droplets in inflammation and cancer

PT Bozza, JPB Viola - … , Leukotrienes and Essential Fatty Acids (PLEFA), 2010 - Elsevier
Accumulation of lipid droplets (also known as lipid bodies or adiposomes) within leukocytes,
epithelial cells, hepatocytes and other non-adipocytic cells is a frequently observed …

The dynamic roles of intracellular lipid droplets: from archaea to mammals

DJ Murphy - Protoplasma, 2012 - Springer
During the past decade, there has been a paradigm shift in our understanding of the roles of
intracellular lipid droplets (LDs). New genetic, biochemical and imaging technologies have …

Leukocyte lipid bodies—biogenesis and functions in inflammation

PT Bozza, KG Magalhães, PF Weller - … (BBA)-Molecular and Cell Biology of …, 2009 - Elsevier
Lipid body accumulation within leukocytes is a common feature in both clinical and
experimental infectious, neoplasic and other inflammatory conditions. Here, we will review …

Emerging roles for lipid droplets in immunity and host-pathogen interactions

HA Saka, R Valdivia - Annual review of cell and developmental …, 2012 - annualreviews.org
Lipid droplets (LDs) are neutral lipid storage organelles ubiquitous to eukaryotic cells. It is
increasingly recognized that LDs interact extensively with other organelles and that they …

Lipid body function in eicosanoid synthesis: an update

PT Bozza, I Bakker-Abreu, RA Navarro-Xavier… - … and essential fatty acids …, 2011 - Elsevier
Eicosanoids (prostaglandins, leukotrienes and lipoxins) are signaling lipids derived from
arachidonic acid metabolism that have important roles in physiological and pathological …

Mycobacterium bovis bacillus Calmette-Guerin induces TLR2-mediated formation of lipid bodies: intracellular domains for eicosanoid synthesis in vivo

H D'Avila, RCN Melo, GG Parreira… - The Journal of …, 2006 - journals.aai.org
Differentiation of macrophages into foamy (lipid-laden) macrophages is a common
pathological observation in tuberculous granulomas both in experimental settings as well as …

Cross-kingdom lipid transfer in arbuscular mycorrhiza symbiosis and beyond

A Keymer, C Gutjahr - current opinion in plant biology, 2018 - Elsevier
Highlights•Arbuscular mycorrhiza fungi are likely fatty acid auxotrophs.•Plants maintain an
arbuscular mycorrhiza (AM)-specific lipid biosynthesis pathway.•Independent experimental …

Biogenesis and breakdown of lipid droplets in pathological conditions

CM Fader Kaiser, PS Romano, MC Vanrell… - Frontiers in Cell and …, 2022 - frontiersin.org
Lipid droplets (LD) have long been considered as mere fat drops; however, LD have lately
been revealed to be ubiquitous, dynamic and to be present in diverse organelles in which …