Exploring the current use of animal models in glaucoma drug discovery: where are we in 2023?

R Agarwal, P Agarwal, I Iezhitsa - Expert Opinion on Drug …, 2023 - Taylor & Francis
Introduction Animal models are widely used in glaucoma-related research. Since the
elevated intraocular pressure (IOP) is a major risk factor underlying the disease …

Injectable Hydrogel To Deliver Bone Mesenchymal Stem Cells Preloaded with Azithromycin To Promote Spinal Cord Repair

Y Wan, Y Lin, X Tan, L Gong, F Lei, C Wang, X Sun… - ACS …, 2024 - ACS Publications
Spinal cord injury is a disease that causes severe damage to the central nervous system.
Currently, there is no cure for spinal cord injury. Azithromycin is commonly used as an …

Optic neuropathies: Current and future strategies for optic nerve protection and repair

NR Miller, RK Tsai - International journal of molecular sciences, 2023 - mdpi.com
Processes that damage the optic nerve, including elevated intraocular pressure, trauma,
ischemia, and compression, often cause visual loss for which there is no current treatment. It …

Preventive and therapeutic effects of azithromycin on acrylamide-induced neurotoxicity in rats

HF Kakhki, MG Rahbardar, BM Razavi, MR Heidari… - NeuroToxicology, 2024 - Elsevier
Background Acrylamide (ACR) can induce neurotoxicity through different pathways,
including oxidative stress and apoptosis. Azithromycin is well-known for its antioxidant and …

[HTML][HTML] Effect of astrocyte GPER on the optic nerve inflammatory response following optic nerve injury in mice

X Wang, J Zhou, Y Wang, X Li, Q Hu, L Luo, X Liu… - Heliyon, 2024 - cell.com
Activated astrocytes are a primary source of inflammatory factors following traumatic optic
neuropathy (TON). Accumulation of inflammatory factors in this context leads to increased …

Toxic Medications in Mitochondrial Optic Neuropathies

H Liu, AA Sadun - Advances in Ophthalmology and …, 2023 - advancesinophthalmology.com
Toxic Medications in Mitochondrial Optic Neuropathies - Advances in Ophthalmology and
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