Nano-enabled personalized nutrition: Developing multicomponent-bioactive colloidal delivery systems

DJ McClements - Advances in colloid and interface science, 2020 - Elsevier
There is growing interest in the production of foods and beverages with nutrient and
nutraceutical profiles tailored to an individual's specific nutritional requirements. In principle …

How could metabolomics change pediatric health?

F Bardanzellu, V Fanos - Italian Journal of Pediatrics, 2020 - Springer
In the last years,'omics' technologies, and especially metabolomics, emerged as expanding
scientific disciplines and promising technologies in the characterization of several …

Creation of a milk oligosaccharide database, MilkOligoDB, reveals common structural motifs and extensive diversity across mammals

SD Durham, Z Wei, DG Lemay, MC Lange, D Barile - Scientific reports, 2023 - nature.com
The carbohydrate fraction of most mammalian milks contains a variety of oligosaccharides
that encompass a range of structures and monosaccharide compositions. Human milk …

Dynamic changes in the human milk metabolome over 25 weeks of lactation

KO Poulsen, F Meng, E Lanfranchi, JF Young… - Frontiers in …, 2022 - frontiersin.org
Human milk (HM) provides essential nutrition for ensuring optimal infant growth and
development postpartum. Metabolomics offers insight into the dynamic composition of HM …

Age-related compositional changes and correlations of gut microbiome, serum metabolome, and immune factor in rats

X Zhang, Y Yang, J Su, X Zheng, C Wang, S Chen… - Geroscience, 2021 - Springer
Aging is a complex physiological process associated with degenerative disorder of
metabolism and immune function, which contributes to the occurrence of senile diseases …

The determinants of the human milk metabolome and its role in infant health

A Ojo-Okunola, S Cacciatore, MP Nicol, E du Toit - Metabolites, 2020 - mdpi.com
Human milk is needed for optimal growth as it satisfies both the nutritional and biological
needs of an infant. The established relationship between breastfeeding and an infant's …

Longitudinal multi-omics study of a mother-infant dyad from breastfeeding to weaning: an individualized approach to understand the interactions among diet, fecal …

G Conta, F Del Chierico, S Reddel, F Marini… - Frontiers in Molecular …, 2021 - frontiersin.org
The development of the human gut microbiota is characterized by a dynamic sequence of
events from birth to adulthood, which make the gut microbiota unique for everyone. Its …

Gut microbiota functional traits, blood pH, and anti-GAD antibodies concur in the clinical characterization of T1D at onset

F Del Chierico, G Conta, MC Matteoli… - International Journal of …, 2022 - mdpi.com
Alterations of gut microbiota have been identified before clinical manifestation of type 1
diabetes (T1D). To identify the associations amongst gut microbiome profile, metabolism …

Current practice in untargeted human milk metabolomics

I Ten-Doménech, V Ramos-Garcia, JD Piñeiro-Ramos… - Metabolites, 2020 - mdpi.com
Human milk (HM) is considered the gold standard for infant nutrition. HM contains macro-
and micronutrients, as well as a range of bioactive compounds (hormones, growth factors …

Comprehensive assessment of the diminished statistical power caused by nonlinear electrospray ionization responses in mass spectrometry-based metabolomics

H Yu, T Huan - Analytica chimica acta, 2022 - Elsevier
It seems to be well received that nonlinear electrospray ionization (ESI) distorts the signal
distribution in mass spectrometry (MS) analysis, thus leading to diminished statistical power …