Staging and Classification of Primary Musculoskeletal Bone and Soft-Tissue Tumors According to the 2020 WHO Update, From the AJR Special Series on Cancer …

MD Murphey, MJ Kransdorf - American Journal of …, 2021 - Am Roentgen Ray Soc
Staging of primary musculoskeletal bone and soft-tissue tumors is most commonly
performed using the AJCC and the Enneking or Musculoskeletal Tumor Society (MSTS) …

NTRK‐rearranged spindle cell neoplasms are ubiquitous tumours of myofibroblastic lineage with a distinct methylation class

A Tauziède‐Espariat, M Duchesne, J Baud… - …, 2023 - Wiley Online Library
Aims NTRK gene fusions have been described in a wide variety of central nervous system
(CNS) and soft tissue tumours, including the provisional tumour type 'spindle cell neoplasm …

Interstitial deletions generating fusion genes

I Panagopoulos, S Heim - Cancer Genomics & Proteomics, 2021 - cgp.iiarjournals.org
A fusion gene is the physical juxtaposition of two different genes resulting in a structure
consisting of the head of one gene and the tail of the other. Gene fusion is often a primary …

NTRK-rearranged spindle cell neoplasms: a clinicopathological and molecular study of 13 cases with peculiar characteristics at one of the largest institutions in China

L Yin, C Shi, X He, Y Qiu, H Chen, M Chen, Z Zhang… - Pathology, 2023 - Elsevier
NTRK-rearranged spindle cell neoplasms (NTRK-RSCNs) represent an emerging group of
rare tumours defined using molecular means. To the best of our knowledge, there have …

Primary extradural tumors of the spinal column: A comprehensive treatment guide for the spine surgeon based on the 5: th: Edition of the World Health Organization …

V Arvind, E Nevzati, M Ghaly, M Nasim… - … Junction and Spine, 2021 - journals.lww.com
Background: In 2020, the World Health Organization (WHO) published the 5 th version of the
soft tissue and bone tumor classification. Based on this novel classification system, we …

[HTML][HTML] Update on superficial spindle cell mesenchymal tumors in children

P Drabent, S Fraitag - Dermatopathology, 2021 - mdpi.com
The diagnosis of cutaneous and subcutaneous spindle cell neoplasms in children is often
challenging and has potential therapeutic and prognostic implications. Although correctly …

[HTML][HTML] Detection of novel tyrosine kinase fusion genes as potential therapeutic targets in bone and soft tissue sarcomas using DNA/RNA-based clinical sequencing

N Hasegawa, T Hayashi, H Niizuma… - Clinical Orthopaedics …, 2024 - journals.lww.com
Background Approximately 1% of clinically treatable tyrosine kinase fusions, including
anaplastic lymphoma kinase, neurotrophic tyrosine receptor kinase, RET proto-oncogene …

Imaging characterization of paediatric tumours with the neurotrophic tyrosine receptor kinase fusion transcript

AL Hermann, L Lemelle, G Pierron… - British Journal of …, 2024 - academic.oup.com
Objectives The neurotrophic tyrosine receptor kinase (NTRK) fusion transcript (FT) is a major
genetic landmark of infantile fibrosarcoma (IFS) and cellular congenital mesoblastic …

Lipofibromatosis‐like neural tumors: Report of a case and review of 73 reported cases

CM Ulschmid, V Singam, A Segura… - Pediatric …, 2023 - Wiley Online Library
Lipofibromatosis‐like neural tumors (LPF‐NTs) are a recently discovered group of spindle
cell tumors defined by the presence of a lipofibromatosis‐like pattern, CD34 and/or S100 …

Implementation of multi-mode nursing insulation program for patients receiving surgery for spine tumor: a propensity score-matched analysis

J Liu, C Gao, H Fu, X Zhou, L Zhang, X Tang, Y Wu… - BMC surgery, 2022 - Springer
Background Spinal tumor surgery usually involved long operation time, large area of soft
tissue resection and long wound, and was prone to hypothermia during the operation …