Biological sequence classification: A review on data and general methods

C Ao, S Jiao, Y Wang, L Yu, Q Zou - Research, 2022 - spj.science.org
With the rapid development of biotechnology, the number of biological sequences has
grown exponentially. The continuous expansion of biological sequence data promotes the …

IF-AIP: a machine learning method for the identification of anti-inflammatory peptides using multi-feature fusion strategy

S Gaffar, MT Hassan, H Tayara, KT Chong - Computers in biology and …, 2024 - Elsevier
Background: The most commonly used therapy currently for inflammatory and autoimmune
diseases is nonspecific anti-inflammatory drugs, which have various hazardous side effects …

[HTML][HTML] Databases and computational methods for the identification of piRNA-related molecules: A survey

C Guo, X Wang, H Ren - Computational and Structural Biotechnology …, 2024 - Elsevier
Piwi-interacting RNAs (piRNAs) are a class of small non-coding RNAs (ncRNAs) that play
important roles in many biological processes and major cancer diagnosis and treatment …

pcPromoter-CNN: a CNN-based prediction and classification of promoters

M Shujaat, A Wahab, H Tayara, KT Chong - Genes, 2020 - mdpi.com
A promoter is a small region within the DNA structure that has an important role in initiating
transcription of a specific gene in the genome. Different types of promoters are recognized …

Multi-scale context aggregation for strawberry fruit recognition and disease phenotyping

T Ilyas, A Khan, M Umraiz, Y Jeong, H Kim - IEEE Access, 2021 - ieeexplore.ieee.org
Timely harvesting and disease identification of strawberry fruits is a major concern for
commercial level cultivators. Failing to harvest the grown strawberries can result in the fruit …

Unlocking the therapeutic potential of drug combinations through synergy prediction using graph transformer networks

W Alam, H Tayara, KT Chong - Computers in Biology and Medicine, 2024 - Elsevier
Drug combinations are frequently used to treat cancer to reduce side effects and increase
efficacy. The experimental discovery of drug combination synergy is time-consuming and …

[HTML][HTML] TS-m6A-DL: Tissue-specific identification of N6-methyladenosine sites using a universal deep learning model

Z Abbas, H Tayara, Q Zou, KT Chong - Computational and structural …, 2021 - Elsevier
The most communal post-transcriptional modification, N6-methyladenosine (m6A), is
associated with a number of crucial biological processes. The precise detection of m6A sites …

[HTML][HTML] Identification of piRNA disease associations using deep learning

SD Ali, H Tayara, KT Chong - Computational and Structural Biotechnology …, 2022 - Elsevier
Piwi-interacting RNAs (piRNAs) play a pivotal role in maintaining genome integrity by
repression of transposable elements, gene stability, and association with various disease …

An efficient lightweight hybrid model with attention mechanism for enhancer sequence recognition

S Aladhadh, SA Almatroodi, S Habib, A Alabdulatif… - Biomolecules, 2022 - mdpi.com
Enhancers are sequences with short motifs that exhibit high positional variability and free
scattering properties. Identification of these noncoding DNA fragments and their strength are …

[HTML][HTML] Identifying DNA N4-methylcytosine sites in the rosaceae genome with a deep learning model relying on distributed feature representation

J Khanal, H Tayara, Q Zou, KT Chong - Computational and Structural …, 2021 - Elsevier
Abstract DNA N4-methylcytosine (4mC), an epigenetic modification found in prokaryotic and
eukaryotic species, is involved in numerous biological functions, including host defense …