Mitochondria-endoplasmic reticulum (ER) contact sites (MERCS) are morpho-functional
units, formed at the loci of close apposition of the ER-forming endomembrane and outer …

Despite a significant focus on the photochemical and photoelectrical mechanisms
underlying photobiomodulation (PBM), its complex functions are yet to be fully elucidated …

An increase in intracellular Ca2+ concentration ([Ca2+] i) controls virtually all endothelial
cell functions and is, therefore, crucial to maintain cardiovascular homeostasis. An aberrant …

Store-operated Ca2+ entry (SOCE) is activated in response to the inositol-1, 4, 5-
trisphosphate (InsP3)-dependent depletion of the endoplasmic reticulum (ER) Ca2+ store …

N-methyl-D-aspartate receptors (NMDARs) are ligand-gated ion channels that are activated
by the neurotransmitter glutamate, mediate the slow component of excitatory …

Nitric oxide (NO) represents a crucial mediator to regulate cerebral blood flow (CBF) in the
human brain both under basal conditions and in response to somatosensory stimulation. An …

Cytosolic Ca2+ signals are organized in complex spatial and temporal patterns that underlie
their unique ability to regulate multiple cellular functions. Changes in intracellular Ca2+ …

Every blood vessel is lined by a single layer of highly specialized, yet adaptable and
multifunctional endothelial cells. These cells, the endothelium, control vascular contractility …

The adrenal gland is an essential component of the body stress response; it is formed by two
portions: a steroidogenic and a chromaffin tissue. Despite the anatomy of adrenal gland is …

The excitatory neurotransmitter glutamate gates post-synaptic N-methyl-d-aspartate (NMDA)
receptors (NMDARs) to mediate extracellular Ca 2+ entry and stimulate neuronal nitric oxide …