Pubertal development and regulation

AP Abreu, UB Kaiser - The lancet Diabetes & endocrinology, 2016 - thelancet.com
Puberty marks the end of childhood and is a period when individuals undergo physiological
and psychological changes to achieve sexual maturation and fertility. The hypothalamic …

Cellular and molecular features of EDC exposure: consequences for the GnRH network

D Lopez-Rodriguez, D Franssen, J Bakker… - Nature Reviews …, 2021 - nature.com
The onset of puberty and the female ovulatory cycle are important developmental milestones
of the reproductive system. These processes are controlled by a tightly organized network of …

[PDF][PDF] Desarrollo durante la adolescencia. Aspectos físicos, psicológicos y sociales

M Güemes-Hidalgo, MJ Ceñal González-Fierro… - Pediatría …, 2017 - pediatriaintegral.es
Mientras que la pubertad es un periodo de cambios exclusivamente biológicos, la
adolescencia es el periodo de tiempo entre el inicio de la pubertad y el final del crecimiento …

[PDF][PDF] Pubertad y adolescencia

M Güemes-Hidalgo, M Ceñal… - Revista de formación …, 2017 - academia.edu
In this chapter the differences between puberty and adolescence are exposed, puberty is a
biological event and its definition purely obeys statistical criteria. Adolescence is a broader …

Connecting metabolism and gonadal function: novel central neuropeptide pathways involved in the metabolic control of puberty and fertility

M Manfredi-Lozano, J Roa, M Tena-Sempere - Frontiers in …, 2018 - Elsevier
Albeit essential for perpetuation of species, reproduction is an energy-demanding function
that can be adjusted to body metabolic status. Reproductive maturation and function can be …

[HTML][HTML] Kisspeptins and the neuroendocrine control of reproduction: Recent progress and new frontiers in kisspeptin research

V Sobrino, MS Avendano, C Perdices-Lopez… - Frontiers in …, 2022 - Elsevier
In late 2003, a major breakthrough in our understanding of the mechanisms that govern
reproduction occurred with the identification of the reproductive roles of kisspeptins …

Control central de la temperatura corporal y sus alteraciones: fiebre, hipertermia e hipotermia

YA Picón Jaimes, JE Orozco Chinome, J Molina Franky… - 2020 - repository.unab.edu.co
En mamíferos, el control de la temperatura corporal es vital. El estado de consciencia y
control motor en humanos, ocurren a una temperatura de 37° C y las desviaciones pueden …

SIRT1 mediates obesity- and nutrient-dependent perturbation of pubertal timing by epigenetically controlling Kiss1 expression

MJ Vazquez, CA Toro, JM Castellano… - Nature …, 2018 - nature.com
Puberty is regulated by epigenetic mechanisms and is highly sensitive to metabolic and
nutritional cues. However, the epigenetic pathways mediating the effects of nutrition and …

Central precocious puberty, functional and tumor-related

L Soriano-Guillén, J Argente - … practice & research Clinical endocrinology & …, 2019 - Elsevier
Precocious puberty is defined as the appearance of secondary sex characteristics before 8
years of age in girls and before 9 years of age in boys. Central precocious puberty (CPP) is …

GnRH neurons recruit astrocytes in infancy to facilitate network integration and sexual maturation

G Pellegrino, M Martin, C Allet, T Lhomme… - Nature …, 2021 - nature.com
Neurons that produce gonadotropin-releasing hormone (GnRH), which control fertility,
complete their nose-to-brain migration by birth. However, their function depends on …