Mucin-type O-glycans are a class of glycans initiated with N-acetylgalactosamine (GalNAc) α-
linked primarily to Ser/Thr residues within glycoproteins and often extended or branched by …

Tumour development is usually associated with changes in cell surface carbohydrates.
These are often divided into changes related to terminal carbohydrate structures, which …

Abstract The oncofetal Thomsen–Friedenreich carbohydrate antigen (Galβ1-3GalNAcα1-
Ser/Thr TF or T antigen) is a pan-carcinoma antigen highly expressed by about 90% of all …

Alteration of the expression of carbohydrate structures is frequently observed in tumor cells.
This review summarizes the different changes of O‐and N‐linked glycoproteins observed in …

A broad variety of normal human tissues were examined for the expression of Thomsen-
Friedenreich (TF)-related histo-blood group antigens. TF (Galβ1-3Gal N Acα1-R), Tn (TF …

Little is known on the expression of the tumour-associated carbohydrate antigen sialyl-Tn
(STn), in bladder cancer. We report here that 75% of the high-grade bladder tumours …

Background The T antigen is a tumor-associated structure whose sialylated form (the sialyl-T
antigen) involves the altered expression of sialyltransferases and has been related with …

Bladder carcinogenesis and tumour progression is accompanied by profound alterations in
protein glycosylation on the cell surface, which may be explored for improving disease …

Despite significant worldwide investment in research, cancer remains one of the most
common cause of death in the world. Early detection and reliable diagnosis are the keys to …

T AND Tn SPECIFICITIES were associated with carcinoma for the first time by Springer and
coworkers 1, 2 a quarter of a century ago; however, these specificities were well known to …