It is estimated that 20% to 30% of colorectal cancers (CRCs) are familial with 5% to 10%
related to a known genetic syndrome. 1, 2 The hereditary CRCs are broadly divided into …

Aims: The genetic abnormality known as microsatellite instability (MSI), first identified in
colorectal cancer in 1993, has subsequently been recognised in other malignancies. These …

Abstract Updates to the American Cancer Society (ACS) guidelines regarding screening for
the early detection of prostate, colorectal, and endometrial cancers, based on the …

Epidemiologic patterns of colorectal cancer (CRC) in Iran have not been studied adequately.
In a recent cancer registry and active cancer surveillance, we collected data on the …

Background Colorectal cancer (CRC) is one of the most common cancers worldwide. But
information regarding CRC in Iran is limited; the aim of this study was to investigate the …

PURPOSE: Little is known about colorectal cancer in young patients at a population level,
and the behavior, characteristics, and prognosis of such tumors continue to be debated …

Background Colorectal cancer is one of the most common cancers worldwide and its
incidence is reported to be increasing in resource-limited countries, probably due to the …

Colorectal cancer (CRC) is the third most common cause of cancer death in the world. The
incidence rate (ASR) and age distribution of this disease differ between most of African …

Colorectal cancer (CRC) develops as a multi-step process which results from gradual
accumulation of mutations in proto-oncogenes, tumor suppressor, and DNA repair genes …

AIM: To study the clinical characteristics of hereditary nonpolyposis colorectal cancer
(HNPCC) in the Chinese population and discuss the identification and management of the …