Extracellular vesicles (EVs) are biological nanoparticles naturally secreted by cells, acting
as delivery vehicles for molecular messages. During the last decade, EVs have been …

Despite substantial clinical advances over the past 65 years, cardiovascular disease
remains the leading cause of death in America. The past 15 years has witnessed major …

Mesenchymal stem/stromal cells (MSCs) comprise a heterogeneous population of cells with
multilineage differentiation potential, the ability to modulate oxidative stress, and secrete …

Mesenchymal stem cells (MSCs) are broadly distributed cells that retain postnatal capacity
for self-renewal and multilineage differentiation. MSCs evade immune detection, secrete an …

Stem cells are the seeds of tissue repair and regeneration and a promising source for novel
therapies. However, apart from hematopoietic stem cell (HSC) transplantation, essentially all …

The generation and shedding of extracellular vesicles (EVs), including exosomes and
microvesicles (MVs), by cells has emerged as a form of intercellular communication with …

Hypoxia‐mimetic agents are new potential tools in MSC priming instead of hypoxia
incubators or chambers. Several pharmaceutical/chemical hypoxia‐mimetic agents can be …

Despite considerable progress over the last decades, acute myocardial infarction continues
to remain the major cause of morbidity and mortality worldwide. The present therapies …

Prolonged life expectancy, life style and environmental changes have caused a changing
disease pattern in developed countries towards an increase of degenerative and …

It has been demonstrated that some commonly used Extracellular Vesicle (EV) isolation
techniques can lead to substantial contamination with non-EV factors. Whilst it has been …