[HTML][HTML] Origin of antibiotics and antibiotic resistance, and their impacts on drug development: A narrative review

G Muteeb, MT Rehman, M Shahwan, M Aatif - Pharmaceuticals, 2023 - mdpi.com
Antibiotics have revolutionized medicine, saving countless lives since their discovery in the
early 20th century. However, the origin of antibiotics is now overshadowed by the alarming …

[HTML][HTML] Synthesis of tetracyclic spirooxindolepyrrolidine-engrafted hydantoin scaffolds: crystallographic analysis, molecular docking studies and evaluation of their …

A Toumi, FIA Abdella, S Boudriga, TYA Alanazi… - Molecules, 2023 - mdpi.com
In a sustained search for novel potential drug candidates with multispectrum therapeutic
application, a series of novel spirooxindoles was designed and synthesized via …

[HTML][HTML] The COVID-19 pandemic impact of hospital wastewater on aquatic systems in Bucharest

AR Banciu, LF Pascu, DM Radulescu, C Stoica… - Water, 2024 - mdpi.com
The COVID-19 pandemic reshaped the global response to a pandemic, including the way of
using chemical compounds such as disinfectants and antibiotics. The large-scale use of …

[HTML][HTML] Antibacterial, Antifungal, and Antiviral Bioactive Compounds from Natural Products

X Song - Molecules, 2024 - mdpi.com
In the relentless pursuit of innovative therapeutic agents, natural products have emerged as
a transformative avenue in the battle against infectious diseases. This Special Issue, entitled …

[HTML][HTML] Shorter and Longer Antibiotic Durations for Respiratory Infections: To Fight Antimicrobial Resistance—A Retrospective Cross-Sectional Study in a Secondary …

R Abdelsalam Elshenawy, N Umaru, Z Aslanpour - Pharmaceuticals, 2024 - mdpi.com
As antimicrobial resistance (AMR) escalates globally, examining antibiotic treatment
durations for respiratory infections becomes increasingly pertinent, especially in the context …

[HTML][HTML] Frequency and Antimicrobial Resistance Patterns of Foodborne Pathogens in Ready-to-Eat Foods: An Evolving Public Health Challenge

A Abalkhail - Applied Sciences, 2023 - mdpi.com
Food products that are ready-to-eat have become increasingly popular in recent years due
to their efficiency, affordability, and convenience. However, there are concerns about public …

[HTML][HTML] Photodynamic Antibacterial Therapy of Gallic Acid-Derived Carbon-Based Nanoparticles (GACNPs): Synthesis, Characterization, and Hydrogel Formulation

K Dechsri, C Suwanchawalit, P Patrojanasophon… - Pharmaceutics, 2024 - mdpi.com
Carbon-based nanoparticles (CNPs) have gained recognition because of their good
biocompatibility, easy preparation, and excellent phototherapy properties. In biomedicine …

[HTML][HTML] Genomic Epidemiology Dataset for the Important Nosocomial Pathogenic Bacterium Acinetobacter baumannii

A Shelenkov, Y Mikhaylova, V Akimkin - Data, 2024 - mdpi.com
The infections caused by various bacterial pathogens both in clinical and community
settings represent a significant threat to public healthcare worldwide. The growing …

[HTML][HTML] Antimicrobial Resistance and Antibiotic Consumption in a Secondary Care Hospital in Mexico

EC Dávila-López, MG Berumen-Lechuga… - Antibiotics, 2024 - mdpi.com
Background: Antimicrobial resistance is a global health problem, due to morbidity, mortality,
and healthcare costs. The misuse of antimicrobials is the main cause of antimicrobial …

[HTML][HTML] Antimicrobial Sales Comparison before and after the Implementation of Nationwide Restriction Policy in Saudi Arabia

SM Alajel, KO Alzahrani, AA Almohisen, MM Alrasheed… - Antibiotics, 2023 - mdpi.com
Antimicrobial dispensing without a prescription has been identified as a significant
contributor to the burgeoning crisis of antimicrobial resistance. To combat this, the Saudi …